Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

by Kowalczyk, Monika S., Tirosh, Itay, Heckl, Dirk, Rao, Tata Nageswara, Dixit, Atray, Haas, Brian J., Schneider, Rebekka K., Wagers, Amy J., Ebert, Benjamin L., Regev, Aviv
Published 2016

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

by Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M, Herbst, Rebecca H, Ye, Chun Jimmie, Przybylski, Dariusz, Tirosh, Itay, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A, Hacohen, Nir, Regev, Aviv, Dixit, Atray C., Platt, Randall Jeffrey, Sanjana, Neville E, Shalem, Ophir, Zhang, Feng
Published 2017

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

by Macosko, Evan Z, Satija, Rahul, Nemesh, James, Shekhar, Karthik, Goldman, Melissa, Tirosh, Itay, Bialas, Allison R, Kamitaki, Nolan, Martersteck, Emily M, Trombetta, John J, Weitz, David A, Sanes, Joshua R, McCarroll, Steven A, Shalek, Alexander K, Regev, Aviv, Basu, Anindita 1978-
Published 2017

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

by Puram, Sidharth V., Tirosh, Itay, Parikh, Anuraag S., Patel, Anoop P., Yizhak, Keren, Gillespie, Shawn, Rodman, Christopher, Luo, Christina L., Mroz, Edmund A., Emerick, Kevin S., Deschler, Daniel G., Varvares, Mark A., Mylvaganam, Ravi, Rozenblatt-Rosen, Orit, Rocco, James W., Faquin, William C., Lin, Derrick T., Regev, Aviv, Bernstein, Bradley E.
Published 2018

A single-cell survey of the small intestinal epithelium

by Haber, Adam L., Biton, Moshe, Rogel, Noga, Herbst, Rebecca H., Shekhar, Karthik, Smillie, Christopher, Burgin, Grace, Delorey, Toni M., Howitt, Michael R., Katz, Yarden, Tirosh, Itay, Beyaz, Semir, Dionne, Danielle, Zhang, Mei, Raychowdhury, Raktima, Garrett, Wendy S., Rozenblatt-Rosen, Orit, Shi, Hai Ning, Yilmaz, Omer, Xavier, Ramnik J., Regev, Aviv
Published 2018

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

by Suvà, Mario L, Rheinbay, Esther, Gillespie, Shawn M, Patel, Anoop P, Wakimoto, Hiroaki, Rabkin, Samuel D, Riggi, Nicolo, Chi, Andrew S, Cahill, Daniel P, Nahed, Brian V, Curry, William T, Martuza, Robert L, Rivera, Miguel N, Rossetti, Nikki, Kasif, Simon, Beik, Samantha, Kadri, Sabah, Tirosh, Itay, Wortman, Ivo, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Louis, David N, Bernstein, Bradley E
Published 2017

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

by Biton, Moshe, Haber, Adam L., Rogel, Noga, Burgin, Grace, Beyaz, Semir, Schnell, Alexandra, Ashenberg, Orr, Su, Chien-Wen, Smillie, Christopher, Shekhar, Karthik, Chen, Zuojia, Wu, Chuan, Ordovas-Montanes, Jose Manuel, Alvarez, David, Herbst, Rebecca H., Zhang, Mei, Tirosh, Itay, Dionne, Danielle, Nguyen, Lan T., Xifaras, Michael, Shalek, Alexander K, von Andrian, Ulrich H., Graham, Daniel B., Rozenblatt-Rosen, Orit, Shi, Hai Ning, Kuchroo, Vijay, Yilmaz, Omer, Regev, Aviv, Xavier, Ramnik Joseph
Published 2020

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

by Nirschl, Christopher J., Suárez-Fariñas, Mayte, Izar, Benjamin, Dannenfelser, Ruth, Tirosh, Itay, Liu, Yong, Zhu, Qian, Devi, K. Sanjana P., Chau, David, Rezaee, Melika, Kim, Tae-Gyun, Huang, Ruiqi, Fuentes-Duculan, Judilyn, Song-Zhao, George X., Gulati, Nicholas, Lowes, Michelle A., King, Sandra L., Quintana, Francisco J., Lee, Young-suk, Krueger, James G., Sarin, Kavita Y., Yoon, Charles H., Troyanskaya, Olga, Anandasabapathy, Niroshana, Prakadan, Sanjay, Carroll, Shaina Laufer, Regev, Aviv, Shalek, Alexander K, Garraway, Levi A.
Published 2018

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

by Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Brastianos, Priscilla K., Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Suvà, Mario L., Dionne, Danielle, Golub, Todd, Getz, Gad Asher, Regev, Aviv, Bernstein, Bradley E.
Published 2018

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

by Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Suvà, Mario L., Golub, Todd, Regev, Aviv
Published 2018

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

by Jerby-Arnon, Livnat, Shah, Parin, Cuoco, Michael S., Rodman, Christopher, Su, Mei-Ju, Melms, Johannes C., Leeson, Rachel, Kanodia, Abhay, Mei, Shaolin, Lin, Jia-Ren, Wang, Shu, Rabasha, Bokang, Liu, David, Zhang, Gao, Margolais, Claire, Ashenberg, Orr, Ott, Patrick A., Buchbinder, Elizabeth I., Haq, Rizwan, Hodi, F. Stephen, Boland, Genevieve M., Sullivan, Ryan J., Frederick, Dennie T., Miao, Benchun, Moll, Tabea, Flaherty, Keith T., Herlyn, Meenhard, Jenkins, Russell W., Thummalapalli, Rohit, Kowalczyk, Monika S., Cañadas, Israel, Schilling, Bastian, Cartwright, Adam N.R, Luoma, Adrienne M., Malu, Shruti, Hwu, Patrick, Bernatchez, Chantale, Forget, Marie-Andrée, Barbie, David A., Shalek, Alex K., Tirosh, Itay, Sorger, Peter K., Wucherpfennig, Kai, Van Allen, Eliezer M., Schadendorf, Dirk, Johnson, Bruce E., Rotem, Asaf, Rozenblatt-Rosen, Orit, Garraway, Levi A., Yoon, Charles H., Izar, Benjamin, Regev, Aviv
Published 2020

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

by Keskin, Derin B., Anandappa, Annabelle J., Sun, Jing, Tirosh, Itay, Mathewson, Nathan D., Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet A., Hu, Zhuting, Li, Letitia, Le, Phuong M., Allesøe, Rosa L., Richman, Alyssa R., Kowalczyk, Monika S., Abdelrahman, Sara, Geduldig, Jack E., Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J. Bryan, Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars R., Stevens, Jonathan, Lane, William J., Salazar, Andres M., Daley, Heather, Wen, Patrick Y., Chiocca, E. Antonio, Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Getz, Gad Asher, Lander, Eric Steven, Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott J., Ligon, Keith L., Suvà, Mario L., Wucherpfennig, Kai W., Hacohen, Nir, Fritsch, Edward F., Livak, Kenneth J., Ott, Patrick A., Wu, Catherine J., Reardon, David A.
Published 2020