Moving Beyond the Mouse: Key New Insight Into Human Colonic Dendritic Cells

by Timothy L. Denning, PhD
Published 2016-01-01

Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis

by Hirohito Abo, Kyle L. Flannigan, Duke Geem, Vu L. Ngo, Akihito Harusato, Timothy L. Denning
Published 2019-03-01

Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell CompartmentSummary

by Duke Geem, Vu Ngo, Akihito Harusato, Benoit Chassaing, Andrew T. Gewirtz, Rodney D. Newberry, Timothy L. Denning
Published 2016-05-01

Lactobacillus rhamnosus (LGG) regulates IL-10 signaling in the developing murine colon through upregulation of the IL-10R2 receptor subunit.

by Julie Mirpuri, Ilya Sotnikov, Loren Myers, Timothy L Denning, Felix Yarovinsky, Charles A Parkos, Patricia W Denning, Nancy A Louis
Published 2012-01-01

PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells

by Mingcan Yu, Abdul Malik Tyagi, Jau-Yi Li, Jonathan Adams, Timothy L. Denning, M. Neale Weitzmann, Rheinallt M. Jones, Roberto Pacifici
Published 2020-01-01

“Western Diet”-Induced Adipose Inflammation Requires a Complex Gut MicrobiotaSummary

by Hao Q. Tran, Alexis Bretin, Aneseh Adeshirlarijaney, Beng San Yeoh, Matam Vijay-Kumar, Jun Zou, Timothy L. Denning, Benoit Chassaing, Andrew T. Gewirtz
Published 2020-01-01

Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration

by Hirohito Abo, Benoit Chassaing, Akihito Harusato, Miguel Quiros, Jennifer C. Brazil, Vu L. Ngo, Emilie Viennois, Didier Merlin, Andrew T. Gewirtz, Asma Nusrat, Timothy L. Denning
Published 2020-01-01

Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis.

by Jörn-Hendrik Weitkamp, Michael J Rosen, Zhiguo Zhao, Tatsuki Koyama, Duke Geem, Timothy L Denning, Michael T Rock, Daniel J Moore, Melissa D Halpern, Pranathi Matta, Patricia W Denning
Published 2014-01-01

Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment

by Aliyah M. Weinstein, Lu Chen, Emily A. Brzana, Prashanti R. Patil, Jennifer L. Taylor, Kellsye L. Fabian, Callen T. Wallace, Sabrina D. Jones, Simon C. Watkins, Binfeng Lu, David F. Stroncek, Timothy L. Denning, Yang-Xin Fu, Peter A. Cohen, Walter J. Storkus
Published 2017-06-01