Model-based optimization of the primary drying phase of oral lyophilizates

by Brecht Vanbillemont, Thomas De Beer
Published 2020-12-01

Model-Based Optimisation and Control Strategy for the Primary Drying Phase of a Lyophilisation Process

by Brecht Vanbillemont, Niels Nicolaï, Laurens Leys, Thomas De Beer
Published 2020-02-01

Predicting Pharmaceutical Particle Size Distributions Using Kernel Mean Embedding

by Daan Van Hauwermeiren, Michiel Stock, Thomas De Beer, Ingmar Nopens
Published 2020-03-01

The large N limit of OPEs in symmetric orbifold CFTs with N $$ \mathcal{N} $$ = (4, 4) supersymmetry

by Thomas de Beer, Benjamin A. Burrington, Ian T. Jardine, A.W. Peet
Published 2019-08-01

Mathematical Modelling and Simulation of a Spray Fluidized Bed Granulator

by Gurmeet Kaur, Mehakpreet Singh, Jitendra Kumar, Thomas De Beer, Ingmar Nopens
Published 2018-10-01

Particle-Scale Modeling to Understand Liquid Distribution in Twin-Screw Wet Granulation

by Ashish Kumar, Stefan Radl, Krist V. Gernaey, Thomas De Beer, Ingmar Nopens
Published 2021-06-01

In-Situ X-ray Imaging Of Sublimating Spin-Frozen Solutions

by Wannes Goethals, Brecht Vanbillemont, Joris Lammens, Thomas De Beer, Chris Vervaet, Matthieu N. Boone
Published 2020-07-01

4D Micro-Computed X-ray Tomography as a Tool to Determine Critical Process and Product Information of Spin Freeze-Dried Unit Doses

by Brecht Vanbillemont, Joris Lammens, Wannes Goethals, Chris Vervaet, Matthieu N. Boone, Thomas De Beer
Published 2020-05-01

Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis

by Ana Alejandra Barrera Jiménez, Daan Van Hauwermeiren, Michiel Peeters, Thomas De Beer, Ingmar Nopens
Published 2021-05-01

The Influence of Equipment Design and Process Parameters on Granule Breakage in a Semi-Continuous Fluid Bed Dryer after Continuous Twin-Screw Wet Granulation

by Alexander Ryckaert, Michael Ghijs, Christoph Portier, Dejan Djuric, Adrian Funke, Chris Vervaet, Thomas De Beer
Published 2021-02-01

Analysis of the Effects of Process Parameters on Start-Up Operation in Continuous Wet Granulation

by Kensaku Matsunami, Alexander Ryckaert, Michiel Peeters, Sara Badr, Hirokazu Sugiyama, Ingmar Nopens, Thomas De Beer
Published 2021-08-01

Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

by Lise Vandevivere, Maxine Vangampelaere, Christoph Portier, Cedrine de Backere, Olaf Häusler, Thomas De Beer, Chris Vervaet, Valérie Vanhoorne
Published 2021-02-01

Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy

by Lærke Arnfast, Jeroen van Renterghem, Johanna Aho, Johan Bøtker, Dhara Raijada, Stefania Baldursdóttir, Thomas De Beer, Jukka Rantanen
Published 2020-02-01

Continuous twin screw granulation: Impact of microcrystalline cellulose batch-to-batch variability during granulation and drying – A QbD approach

by Christoph Portier, Tamas Vigh, Giustino Di Pretoro, Jan Leys, Didier Klingeleers, Thomas De Beer, Chris Vervaet, Valérie Vanhoorne
Published 2021-12-01

Inkjet Printing of Drug-Loaded Mesoporous Silica Nanoparticles—A Platform for Drug Development

by Henrika Wickström, Ellen Hilgert, Johan O. Nyman, Diti Desai, Didem Şen Karaman, Thomas de Beer, Niklas Sandler, Jessica M. Rosenholm
Published 2017-11-01

Dynamic Flowsheet Model Development and Sensitivity Analysis of a Continuous Pharmaceutical Tablet Manufacturing Process Using the Wet Granulation Route

by Nirupaplava Metta, Michael Ghijs, Elisabeth Schäfer, Ashish Kumar, Philippe Cappuyns, Ivo Van Assche, Ravendra Singh, Rohit Ramachandran, Thomas De Beer, Marianthi Ierapetritou, Ingmar Nopens
Published 2019-04-01

Surface Functionalization with Polyethylene Glycol and Polyethyleneimine Improves the Performance of Graphene-Based Materials for Safe and Efficient Intracellular Delivery by Laser...

by Jing Liu, Chengnan Li, Toon Brans, Aranit Harizaj, Shana Van de Steene, Thomas De Beer, Stefaan De Smedt, Sabine Szunerits, Rabah Boukherroub, Ranhua Xiong, Kevin Braeckmans
Published 2020-02-01

Assessment and prediction of tablet properties using transmission and backscattering Raman spectroscopy and transmission NIR spectroscopy

by Elisabeth Peeters, Ana Filipa Tavares da Silva, Maunu Toiviainen, Jeroen Van Renterghem, Jurgen Vercruysse, Mikko Juuti, Joao Almeida Lopes, Thomas De Beer, Chris Vervaet, Jean-Paul Remon
Published 2016-08-01

Increasing Angiogenesis Factors in Hypoxic Diabetic Wound Conditions by siRNA Delivery: Additive Effect of LbL-Gold Nanocarriers and Desloratadine-Induced Lysosomal Escape

by Elnaz Shaabani, Maryam Sharifiaghdam, Joris Lammens, Herlinde De Keersmaecker, Chris Vervaet, Thomas De Beer, Elahe Motevaseli, Mohammad Hossein Ghahremani, Parvin Mansouri, Stefaan De Smedt, Koen Raemdonck, Reza Faridi-Majidi, Kevin Braeckmans, Juan C. Fraire
Published 2021-08-01

The generation and use of recombinant extracellular vesicles as biological reference material

by Edward Geeurickx, Joeri Tulkens, Bert Dhondt, Jan Van Deun, Lien Lippens, Glenn Vergauwen, Elisa Heyrman, Delphine De Sutter, Kris Gevaert, Francis Impens, Ilkka Miinalainen, Pieter-Jan Van Bockstal, Thomas De Beer, Marca H. M. Wauben, Esther N. M. Nolte-‘t-Hoen, Katarzyna Bloch, Johannes V. Swinnen, Edwin van der Pol, Rienk Nieuwland, Geert Braems, Nico Callewaert, Pieter Mestdagh, Jo Vandesompele, Hannelore Denys, Sven Eyckerman, Olivier De Wever, An Hendrix
Published 2019-07-01