Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL

by C. Daniel Meyers, Lisa R. Tannock, Thomas N. Wight, Alan Chait
Published 2003-11-01

Oxidized LDL bind to nonproteoglycan components of smooth muscle extracellular matrices

by Mary Y. Chang, Susan Potter-Perigo, Thomas N. Wight, Alan Chait
Published 2001-05-01

Arterial smooth muscle cell proteoglycans synthesized in the presence of glucosamine demonstrate reduced binding to LDL1

by Lisa R. Tannock, Peter J. Little, Thomas N. Wight, Alan Chait
Published 2002-01-01

Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer

by Priyanka Hirani, Valentine Gauthier, Carys E. Allen, Thomas N. Wight, Oliver M. T. Pearce
Published 2021-08-01

Serum amyloid A–containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties

by Chang Yeop Han, Inkyung Kang, Mohamed Omer, Shari Wang, Tomasz Wietecha, Thomas N. Wight, Alan Chait
Published 2020-10-01

Modulation of hyaluronan synthases and involvement of T cell-derived hyaluronan in autoimmune responses to transplanted islets

by John A. Gebe, Michel D. Gooden, Gail Workman, Nadine Nagy, Paul L. Bollyky, Thomas N. Wight, Robert B. Vernon
Published 2021-02-01

Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis.

by Jo Nadine Fleming, Howard M Shulman, Richard A Nash, Pamela Y Johnson, Thomas N Wight, Allen Gown, Stephen M Schwartz
Published 2009-07-01

4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer

by Nadine eNagy, Hedwich F. Kuipers, Adam R. Frymoyer, Heather D. Ishak, Jennifer B. Bollyky, Thomas N. Wight, Paul L. Bollyky
Published 2015-03-01

ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan

by Katherine Olin-Lewis, Ronald M. Krauss, Michael La Belle, Patricia J. Blanche, P.Hugh R. Barrett, Thomas N. Wight, Alan Chait
Published 2002-11-01

Versican—A Critical Extracellular Matrix Regulator of Immunity and Inflammation

by Thomas N. Wight, Inkyung Kang, Stephen P. Evanko, Ingrid A. Harten, Mary Y. Chang, Oliver M. T. Pearce, Carys E. Allen, Charles W. Frevert
Published 2020-03-01

Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts

by Stephen R. Reeves, Inkyung Kang, Christina K. Chan, Kaitlyn A. Barrow, Tessa K. Kolstad, Maria P. White, Steven F. Ziegler, Thomas N. Wight, Jason S. Debley
Published 2018-08-01

Versican is differentially regulated in the adventitial and medial layers of human vein grafts.

by Richard D Kenagy, Shinsuke Kikuchi, Steve P Evanko, Matthijs S Ruiter, Marco Piola, Alban Longchamp, Maurizio Pesce, Monica Soncini, Sébastien Deglise, Gianfranco B Fiore, Jacques-Antoine Haefliger, Tannin A Schmidt, Mark W Majesky, Michael Sobel, Thomas N Wight
Published 2018-01-01

Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity

by Chang Yeop Han, Inkyung Kang, Ingrid A. Harten, John A. Gebe, Christina K. Chan, Mohamed Omer, Kimberly M. Alonge, Laura J. den Hartigh, Diego Gomes Kjerulf, Leela Goodspeed, Savitha Subramanian, Shari Wang, Francis Kim, David E. Birk, Thomas N. Wight, Alan Chait
Published 2020-06-01

Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Protea...

by Stephen R. Reeves, Stephen R. Reeves, Stephen R. Reeves, Kaitlyn A. Barrow, Lucille M. Rich, Maria P. White, Nicholas J. Shubin, Christina K. Chan, Inkyung Kang, Steven F. Ziegler, Adrian M. Piliponsky, Adrian M. Piliponsky, Thomas N. Wight, Jason S. Debley, Jason S. Debley, Jason S. Debley
Published 2020-01-01