Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma

by Connor Rogerson, Samuel Ogden, Edward Britton, The OCCAMS Consortium, Yeng Ang, Andrew D Sharrocks
Published 2020-09-01

Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma.

by Edward Britton, Connor Rogerson, Shaveta Mehta, Yaoyong Li, Xiaodun Li, OCCAMS consortium, Rebecca C Fitzgerald, Yeng S Ang, Andrew D Sharrocks
Published 2017-08-01

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis.

by Daffolyn Rachael Fels Elliott, Juliane Perner, Xiaodun Li, Martyn F Symmons, Brett Verstak, Matthew Eldridge, Lawrence Bower, Maria O'Donovan, Nick J Gay, OCCAMS Consortium, Rebecca C Fitzgerald
Published 2017-05-01

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

by Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi, The Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Francesca D. Ciccarelli
Published 2019-07-01