Use of IFN-Based Biotherapeutics to Harness the Host Against Foot-And-Mouth Disease

by Gisselle N. Medina, Gisselle N. Medina, Teresa de los Santos, Fayna Diaz-San Segundo
Published 2020-08-01

Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80.

by Xiangyu Chen, Robert Gaglione, Trevor Leong, Lauren Bednor, Teresa de Los Santos, Ed Luk, Michael Airola, Nancy M Hollingsworth
Published 2018-11-01

The Different Tactics of Foot-and-Mouth Disease Virus to Evade Innate Immunity

by Gisselle N. Medina, Gisselle N. Medina, Fayna Díaz-San Segundo, Fayna Díaz-San Segundo, Carolina Stenfeldt, Carolina Stenfeldt, Jonathan Arzt, Teresa de los Santos
Published 2018-11-01

Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus

by Fayna Diaz-San Segundo, Gisselle N. Medina, Gisselle N. Medina, Edward Spinard, Edward Spinard, Anna Kloc, Anna Kloc, Elizabeth Ramirez-Medina, Elizabeth Ramirez-Medina, Paul Azzinaro, Steffen Mueller, Elizabeth Rieder, Teresa de los Santos
Published 2021-01-01

Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV

by Fayna Diaz-San Segundo, Gisselle N. Medina, Gisselle N. Medina, Paul Azzinaro, Joseph Gutkoska, Aishwarya Mogulothu, Aishwarya Mogulothu, Sarah E. Attreed, Sarah E. Attreed, Kimberly R. Lombardi, Jacob Shields, Teresa A. Hudock, Teresa de los Santos
Published 2021-05-01

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppres...

by Linda J Visser, Chiara Aloise, Kirby N Swatek, Gisselle N Medina, Karin M Olek, Huib H Rabouw, Raoul J de Groot, Martijn A Langereis, Teresa de Los Santos, David Komander, Tim Skern, Frank J M van Kuppeveld
Published 2020-07-01