Dimensionality of Motion and Binding Valency Govern Receptor–Ligand Kinetics As Revealed by Agent-Based Modeling

by Teresa Lehnert, Teresa Lehnert, Marc Thilo Figge, Marc Thilo Figge, Marc Thilo Figge
Published 2017-11-01

A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood.

by Kerstin Hünniger, Teresa Lehnert, Kristin Bieber, Ronny Martin, Marc Thilo Figge, Oliver Kurzai
Published 2014-02-01

Comparative assessment of immune evasion mechanisms in human whole-blood infection assays by a systems biology approach.

by Teresa Lehnert, Maria T E Prauße, Kerstin Hünniger, Jan-Philipp Praetorius, Oliver Kurzai, Marc Thilo Figge
Published 2021-01-01

Quantitative Simulations Predict Treatment Strategies Against Fungal Infections in Virtual Neutropenic Patients

by Sandra Timme, Sandra Timme, Teresa Lehnert, Teresa Lehnert, Maria T. E. Prauße, Maria T. E. Prauße, Kerstin Hünniger, Kerstin Hünniger, Ines Leonhardt, Ines Leonhardt, Oliver Kurzai, Oliver Kurzai, Oliver Kurzai, Marc Thilo Figge, Marc Thilo Figge, Marc Thilo Figge
Published 2018-04-01

Predictive Virtual Infection Modeling of Fungal Immune Evasion in Human Whole Blood

by Maria T. E. Prauße, Maria T. E. Prauße, Teresa Lehnert, Teresa Lehnert, Sandra Timme, Sandra Timme, Kerstin Hünniger, Kerstin Hünniger, Ines Leonhardt, Ines Leonhardt, Oliver Kurzai, Oliver Kurzai, Oliver Kurzai, Marc Thilo Figge, Marc Thilo Figge, Marc Thilo Figge
Published 2018-03-01

Quantification of Factor H Mediated Self vs. Non-self Discrimination by Mathematical Modeling

by Alexander Tille, Alexander Tille, Teresa Lehnert, Peter F. Zipfel, Peter F. Zipfel, Marc Thilo Figge, Marc Thilo Figge
Published 2020-09-01

Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions

by Teresa Lehnert, Ines Leonhardt, Sandra Timme, Daniel Thomas-Rüddel, Frank Bloos, Christoph Sponholz, Oliver Kurzai, Marc Thilo Figge, Kerstin Hünniger
Published 2021-06-01

Dynamic Interplay of Host and Pathogens in an Avian Whole-Blood Model

by Sravya Sreekantapuram, Teresa Lehnert, Maria T. E. Prauße, Maria T. E. Prauße, Angela Berndt, Christian Berens, Marc Thilo Figge, Marc Thilo Figge, Ilse D. Jacobsen, Ilse D. Jacobsen
Published 2020-03-01