Stress and Vascular Responses: Endothelial Dysfunction via Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1: Close Relationships With Oxidative Stress

by Kanako Sakurai, Tatsuya Sawamura
Published 2003-01-01

Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.

by Takeshi Tomita, Katsuaki Ieguchi, Tatsuya Sawamura, Yoshiro Maru
Published 2015-01-01

Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model

by Marumi Ohno, Akemi Kakino, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Tatsuya Sawamura, Hiroshi Kida
Published 2021-08-01

LOX-1 plays an important role in ischemia-induced angiogenesis of limbs.

by Takeru Shiraki, Takuma Aoyama, Chiharu Yokoyama, Yuka Hayakawa, Toshiki Tanaka, Kazuhiko Nishigaki, Tatsuya Sawamura, Shinya Minatoguchi
Published 2014-01-01

Autoimmune Rheumatic Diseases: An Update on the Role of Atherogenic Electronegative LDL and Potential Therapeutic Strategies

by Der-Yuan Chen, Tatsuya Sawamura, Richard A. F. Dixon, José Luis Sánchez-Quesada, Chu-Huang Chen
Published 2021-05-01

LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma

by David F. Schaeffer, Maziar Riazy, Kuljit S. Parhar, Johnny H. Chen, Vincent Duronio, Tatsuya Sawamura, Urs P. Steinbrecher
Published 2009-08-01

Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase

by Feng Xia Ma, Bin Zhou, Zhong Chen, Qian Ren, Shi Hong Lu, Tatsuya Sawamura, Zhong Chao Han
Published 2006-06-01

Syncytiotrophoblast extracellular vesicles impair rat uterine vascular function via the lectin-like oxidized LDL receptor-1.

by Floor Spaans, Cindy K Kao, Jude S Morton, Anita L Quon, Tatsuya Sawamura, Dionne S Tannetta, Ian L Sargent, Sandra T Davidge
Published 2017-01-01

Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.

by Chiharu Yokoyama, Takuma Aoyama, Takahiro Ido, Akemi Kakino, Takeru Shiraki, Toshiki Tanaka, Kazuhiko Nishigaki, Aiko Hasegawa, Yoshiko Fujita, Tatsuya Sawamura, Shinya Minatoguchi
Published 2016-01-01

Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome

by Tomofumi Misaka, Satoshi Suzuki, Nobuo Sakamoto, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Shu-ichi Saitoh, Tatsuya Sawamura, Toshiyuki Ishibashi, Yasuchika Takeishi
Published 2014-01-01

Atherogenic L5 LDL induces cardiomyocyte apoptosis and inhibits KATP channels through CaMKII activation

by Yanzhuo Ma, Nancy Cheng, Junping Sun, Jonathan Xuhai Lu, Shahrzad Abbasi, Geru Wu, An-Sheng Lee, Tatsuya Sawamura, Jie Cheng, Chu-Huang Chen, Yutao Xi
Published 2020-08-01

The biphasic effects of oxidized-low density lipoprotein on the vasculogenic function of endothelial progenitor cells.

by Feng-Yen Lin, Nai-Wen Tsao, Chun-Ming Shih, Yi-Wen Lin, Jong-Shiua Yeh, Jaw-Wen Chen, Hironori Nakagami, Ryuichi Morishita, Tatsuya Sawamura, Chun-Yao Huang
Published 2015-01-01

Electronegative LDL circulating in smokers impairs endothelial progenitor cell differentiation by inhibiting Akt phosphorylation via LOX-1

by Daming Tang, Jonathan Lu, Jeffrey P. Walterscheid, Hsin-Hung Chen, David A. Engler, Tatsuya Sawamura, Po-Yuan Chang, Hazim J. Safi, Chao-Yuh Yang, Chu-Huang Chen
Published 2008-01-01

Electronegative low-density lipoprotein increases C-reactive protein expression in vascular endothelial cells through the LOX-1 receptor.

by Chih-Sheng Chu, Yu-Chen Wang, Long-Sheng Lu, Brian Walton, H Ramazan Yilmaz, Roger Y Huang, Tatsuya Sawamura, Richard A F Dixon, Wen-Ter Lai, Chu-Huang Chen, Jonathan Lu
Published 2013-01-01

RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane

by Serina Yokoyama, Tatsuo Kawai, Koichi Yamamoto, Huang Yibin, Hiroko Yamamoto, Akemi Kakino, Hikari Takeshita, Yoichi Nozato, Taku Fujimoto, Kazuhiro Hongyo, Toshimasa Takahashi, Futoshi Nakagami, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Tatsuya Sawamura, Hiromi Rakugi
Published 2021-03-01

The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor

by Toshimasa Takahashi, Yibin Huang, Koichi Yamamoto, Go Hamano, Akemi Kakino, Fei Kang, Yuki Imaizumi, Hikari Takeshita, Yoichi Nozato, Satoko Nozato, Serina Yokoyama, Motonori Nagasawa, Tatsuo Kawai, Masao Takeda, Taku Fujimoto, Kazuhiro Hongyo, Futoshi Nakagami, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Herbert Y. Gaisano, Tatsuya Sawamura, Hiromi Rakugi
Published 2021-02-01