Differential Role of TGF-β in Extracellular Matrix Regulation During <i>Trypanosoma cruzi</i>-Host Cell Interaction

by Tatiana Araújo Silva, Luis Felipe de Carvalho Ferreira, Mirian Claudia de Souza Pereira, Claudia Magalhães Calvet
Published 2019-09-01

Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole.

by Claudia Magalhães Calvet, Tatiana Araújo Silva, Diane Thomas, Brian Suzuki, Ken Hirata, Jair Lage Siqueira-Neto, James H McKerrow
Published 2020-09-01

Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways.

by Jacob M Wozniak, Tatiana Araújo Silva, Diane Thomas, Jair L Siqueira-Neto, James H McKerrow, David J Gonzalez, Claudia M Calvet
Published 2020-05-01

4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi inf...

by Claudia Magalhaes Calvet, Jun Yong Choi, Diane Thomas, Brian Suzuki, Ken Hirata, Sharon Lostracco-Johnson, Liliane Batista de Mesquita, Alanderson Nogueira, Marcelo Meuser-Batista, Tatiana Araujo Silva, Jair Lage Siqueira-Neto, William R Roush, Mirian Claudia de Souza Pereira, James H McKerrow, Larissa M Podust
Published 2017-12-01