The Sweat Metabolome of Screen-Positive Cystic Fibrosis Infants: Revealing Mechanisms beyond Impaired Chloride Transport

by Adriana N. Macedo, Stellena Mathiaparanam, Lauren Brick, Katherine Keenan, Tanja Gonska, Linda Pedder, Stephen Hill, Philip Britz-McKibbin
Published 2017-07-01

The CFTR Mutation c.3453G > C (D1152H) Confers an Anion Selectivity Defect in Primary Airway Tissue that Can Be Rescued by Ivacaftor

by Onofrio Laselva, Theo J. Moraes, Gengming He, Claire Bartlett, Ida Szàrics, Hong Ouyang, Tarini N. A. Gunawardena, Lisa Strug, Christine E. Bear, Tanja Gonska
Published 2020-05-01

Preclinical Studies of a Rare CF-Causing Mutation in the Second Nucleotide Binding Domain (c.3700A>G) Show Robust Functional Rescue in Primary Nasal Cultures by Novel CFTR Modulato...

by Onofrio Laselva, Jacqueline McCormack, Claire Bartlett, Wan Ip, Tarini N. A. Gunawardena, Hong Ouyang, Paul D. W. Eckford, Tanja Gonska, Theo J. Moraes, Christine E. Bear
Published 2020-11-01

Testing gene therapy vectors in human primary nasal epithelial cultures

by Huibi Cao, Hong Ouyang, Wan Ip, Kai Du, Wenming Duan, Julie Avolio, Jing Wu, Cathleen Duan, Herman Yeger, Christine E Bear, Tanja Gonska, Jim Hu, Theo J Moraes
Published 2015-01-01

A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition

by Ines Loverdos, Marc C. Swan, Shant Shekherdimian, Abdulrahman A. Al-Rasheed, Rayfel Schneider, Joel S. Fish, Bo-Yee Ngan, Khosrow Adeli, Mark E. Lowe, Vijay P. Singh, Wednesday Marie A. Sevilla, Jacob C. Langer, Tanja Gonska
Published 2015-05-01

Immunoreactive trypsinogen levels in newborn screened infants with an inconclusive diagnosis of cystic fibrosis

by Chee Y. Ooi, Rosie Sutherland, Carlo Castellani, Katherine Keenan, Margaret Boland, Joe Reisman, Candice Bjornson, Mark A. Chilvers, Richard van Wylick, Steven Kent, April Price, Dimas Mateos-Corral, Daniel Hughes, Melinda Solomon, Peter Zuberbuhler, Janna Brusky, Peter R. Durie, Felix Ratjen, Tanja Gonska
Published 2019-10-01

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

by Saumel Ahmadi, Zoltan Bozoky, Michelle Di Paola, Sunny Xia, Canhui Li, Amy P. Wong, Leigh Wellhauser, Steven V. Molinski, Wan Ip, Hong Ouyang, Julie Avolio, Julie D. Forman-Kay, Felix Ratjen, Jeremy A. Hirota, Johanna Rommens, Janet Rossant, Tanja Gonska, Theo J. Moraes, Christine E. Bear
Published 2017-04-01