Transformation from adenocarcinoma to squamous cell lung carcinoma with MET amplification after lorlatinib resistance: A case report

by Shoko Ueda, Takehito Shukuya, Takuo Hayashi, Mario Suzuki, Akihide Kondo, Yuta Arai, Tomohito Takeshige, Hironori Ninomiya, Kazuhisa Takahashi
Published 2021-03-01

Impact of the generation of EGFR‐TKIs administered as prior therapy on the efficacy of osimertinib in patients with non‐small cell lung cancer harboring EGFR T790M mutation

by Yosuke Miyashita, Ryo Ko, Naoko Shimada, Yoichiro Mitsuishi, Keita Miura, Naohisa Matsumoto, Tetsuhiko Asao, Takehito Shukuya, Rina Shibayama, Ryo Koyama, Kazuhisa Takahashi
Published 2021-02-01

Hermansky-Pudlak syndrome-associated pneumothorax with rapid progression of respiratory failure: a case report

by Yukari Kato, Motoyasu Kato, Hiroaki Ihara, Eri Hayakawa, Kohei Shibayama, Keita Miura, Tomoko Yamada, Yoichiro Mitsuishi, Takehito Shukuya, Jun Ito, Takeshi Matsunaga, Tadashi Sato, Kenji Suzuki, Kazuhisa Takahashi
Published 2020-10-01

Progression-free survival, post-progression survival, and tumor response as surrogate markers for overall survival in patients with extensive small cell lung cancer

by Hisao Imai, Keita Mori, Kazushige Wakuda, Akira Ono, Hiroaki Akamatsu, Takehito Shukuya, Tetsuhiko Taira, Hirotsugu Kenmotsu, Tateaki Naito, Kyoichi Kaira, Haruyasu Murakami, Masahiro Endo, Takashi Nakajima, Nobuyuki Yamamoto, Toshiaki Takahashi
Published 2015-01-01

Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study

by Kota Nakamura, Motoyasu Kato, Takehito Shukuya, Keita Mori, Yasuhito Sekimoto, Hiroaki Ihara, Ryota Kanemaru, Ryo Ko, Rina Shibayama, Ken Tajima, Ryo Koyama, Naoko Shimada, Osamu Nagashima, Fumiyuki Takahashi, Shinichi Sasaki, Kazuhisa Takahashi
Published 2017-05-01

Activation of insulin‐like growth factor‐1 receptor confers acquired resistance to osimertinib in non‐small cell lung cancer with EGFR T790M mutation

by Daisuke Hayakawa, Fumiyuki Takahashi, Yoichiro Mitsuishi, Ken Tajima, Moulid Hidayat, Wira Winardi, Hiroaki Ihara, Koichiro Kanamori, Naohisa Matsumoto, Tetsuhiko Asao, Ryo Ko, Takehito Shukuya, Kazuya Takamochi, Takuo Hayashi, Yoshiyuki Suehara, Ikuko Takeda Nakamura, Toshihide Ueno, Shinji Kohsaka, Hiroyuki Mano, Kazuhisa Takahashi
Published 2020-01-01

Size-based isolation of circulating tumor cells in lung cancer patients using a microcavity array system.

by Masahito Hosokawa, Hirotsugu Kenmotsu, Yasuhiro Koh, Tomoko Yoshino, Takayuki Yoshikawa, Tateaki Naito, Toshiaki Takahashi, Haruyasu Murakami, Yukiko Nakamura, Asuka Tsuya, Takehito Shukuya, Akira Ono, Hiroaki Akamatsu, Reiko Watanabe, Sachiyo Ono, Keita Mori, Hisashige Kanbara, Ken Yamaguchi, Tsuyoshi Tanaka, Tadashi Matsunaga, Nobuyuki Yamamoto
Published 2013-01-01

Zinc‐finger E‐box‐binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib

by Fariz Nurwidya, Fumiyuki Takahashi, Wira Winardi, Ken Tajima, Yoichiro Mitsuishi, Akiko Murakami, Isao Kobayashi, Takeshi Nara, Muneaki Hashimoto, Motoyasu Kato, Moulid Hidayat, Kentaro Suina, Daisuke Hayakawa, Tetsuhiko Asao, Ryo Ko, Takehito Shukuya, Toshifumi Yae, Naoko Shimada, Yasuko Yoshioka, Shinichi Sasaki, Kazuhisa Takahashi
Published 2021-05-01

Comparison of Tumor Microenvironments Between Primary Tumors and Brain Metastases in Patients With NSCLC

by Daiki Ikarashi, MD, PhD, Tamio Okimoto, MD, PhD, Takehito Shukuya, MD, PhD, Hiroko Onagi, MD, Takuo Hayashi, MD, PhD, Sara L. Sinicropi-Yao, PhD, Joseph M. Amann, PhD, Tetsuya Nakatsura, MD, PhD, Shigehisa Kitano, MD, PhD, David P. Carbone, MD, PhD
Published 2021-10-01