Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm.

by Takashi Umehara, Natsumi Tsujita, Masayuki Shimada
Published 2019-08-01

Saturated fatty acids accelerate linear motility through mitochondrial ATP production in bull sperm

by Md. Mazharul Islam, Takashi Umehara, Natsumi Tsujita, Masayuki Shimada
Published 2021-07-01

Crystal Structure of LSD1 in Complex with 4-[5-(Piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile

by Hideaki Niwa, Shin Sato, Tomoko Hashimoto, Kenji Matsuno, Takashi Umehara
Published 2018-06-01

Cutting the ovarian surface improves the responsiveness to exogenous hormonal treatment in aged mice

by Takashi Umehara, Nao Urabe, Toshiki Obata, Takashi Yamaguchi, Atsushi Tanaka, Masayuki Shimada
Published 2020-10-01

Inductions of granulosa cell luteinization and cumulus expansion are dependent on the fibronectin-integrin pathway during ovulation process in mice.

by Hiroya Kitasaka, Tomoko Kawai, S A Masudul Hoque, Takashi Umehara, Youko Fujita, Masayuki Shimada
Published 2018-01-01

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8

by Takeshi Tsusaka, Masaki Kikuchi, Tadahiro Shimazu, Takehiro Suzuki, Yoshihiro Sohtome, Mai Akakabe, Mikiko Sodeoka, Naoshi Dohmae, Takashi Umehara, Yoichi Shinkai
Published 2018-10-01

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling

by Yosuke Yoneyama, Peter Lanzerstorfer, Hideaki Niwa, Takashi Umehara, Takashi Shibano, Shigeyuki Yokoyama, Kazuhiro Chida, Julian Weghuber, Fumihiko Hakuno, Shin-Ichiro Takahashi
Published 2018-04-01

Gene Expression and Protein Synthesis in Mitochondria Enhance the Duration of High-Speed Linear Motility in Boar Sperm

by Zhendong Zhu, Zhendong Zhu, Takashi Umehara, Tetsuji Okazaki, Masaaki Goto, Masaaki Goto, Yoko Fujita, S. A. Masudul Hoque, S. A. Masudul Hoque, Tomoko Kawai, Wenxian Zeng, Masayuki Shimada
Published 2019-03-01

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

by Erna Davydova, Tadahiro Shimazu, Maren Kirstin Schuhmacher, Magnus E. Jakobsson, Hanneke L. D. M. Willemen, Tongri Liu, Anders Moen, Angela Y. Y. Ho, Jędrzej Małecki, Lisa Schroer, Rita Pinto, Takehiro Suzuki, Ida A. Grønsberg, Yoshihiro Sohtome, Mai Akakabe, Sara Weirich, Masaki Kikuchi, Jesper V. Olsen, Naoshi Dohmae, Takashi Umehara, Mikiko Sodeoka, Valentina Siino, Michael A. McDonough, Niels Eijkelkamp, Christopher J. Schofield, Albert Jeltsch, Yoichi Shinkai, Pål Ø. Falnes
Published 2021-02-01