Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells.

by Thomas R Kolodecik, Christine A Shugrue, Edwin C Thrower, Lonny R Levin, Jochen Buck, Fred S Gorelick
Published 2012-01-01

Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice.

by A A Alahmari, B Sreekumar, V Patel, M Ashat, M Alexandre, A K Uduman, E O Akinbiyi, A Ceplenski, C A Shugrue, T R Kolodecik, N Tashkandi, S W Messenger, G E Groblewski, F S Gorelick, E C Thrower
Published 2018-01-01

IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules.

by Abrahim I Orabi, Yuhuan Luo, Mahwish U Ahmad, Ahsan U Shah, Zahir Mannan, Dong Wang, Sheharyar Sarwar, Kamaldeen A Muili, Christine Shugrue, Thomas R Kolodecik, Vijay P Singh, Mark E Lowe, Edwin Thrower, Ju Chen, Sohail Z Husain
Published 2012-01-01