Subjects with molecularly defined familial hypercholesterolemia or familial defective apoB-100 are not being adequately treated.

by Trond P Leren, Knut Erik Berge
Published 2011-02-01

Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reti...

by Thea Bismo Strøm, Kristian Tveten, Jon K. Laerdahl, Trond P. Leren
Published 2014-01-01

PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment

by Kristian Tveten, Thea Bismo Str⊘m, Knut Erik Berge, Trond P. Leren
Published 2013-06-01

Heterozygosity for apolipoprotein A-I(R160L)Oslo is associated with low levels of high density lipoprotein cholesterol and HDL-subclass LpA-I/A-II but normal levels of HDL-subclass...

by T P Leren, K S Bakken, U Daum, L Ose, K Berg, G Assmann, A von Eckardstein
Published 1997-01-01

Phenotypic consequences of a deletion of exons 2 and 3 of the LDL receptor gene

by Olaug K. Rødningen, Serena Tonstad, Jheem D. Medh, David A. Chappell, Leiv Ose, Trond P. Leren
Published 1999-02-01

Multiple dysfunctions of two apolipoprotein A-I variants, apoA-I(R160L)Oslo and apoA-I(P165R), that are associated with hypoalphalipoproteinemia in heterozygous carriers

by Ulrike Daum, Trond P. Leren, Claus Langer, Ali Chirazi, Paul Cullen, P. Haydn Pritchard, Gerd Assmann, Arnold von Eckardstein
Published 1999-03-01

Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors

by Øystein L. Holla, Jamie Cameron, Kristian Tveten, Thea Bismo Str⊘m, Knut Erik Berge, Jon K. Laerdahl, Trond P. Leren
Published 2011-10-01

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

by Anders G. Holst, Kirstine Calloe, Thomas Jespersen, Pernille Cedergreen, Bo G. Winkel, Henrik Kjaerulf Jensen, Trond P. Leren, Stig Haunso, Jesper Hastrup Svendsen, Jacob Tfelt-Hansen
Published 2009-01-01