Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

by Yu, Dou, Suvà, Mario L., Dong, Biqin, Panek, Wojciech K., Xiao, Ting, Wu, Meijing, Han, Yu, Ahmed, Atique U., Balyasnikova, Irina V., Zhang, Hao F., Sun, Cheng, Lesniak, Maciej S., Khan, Omar Fizal, Langer, Robert S, Anderson, Daniel Griffith
Published 2018

Electrical and synaptic integration of glioma into neural circuits

by Venkatesh, Humsa S., Morishita, Wade, Geraghty, Anna C., Silverbush, Dana, Gillespie, Shawn M., Arzt, Marlene, Tam, Lydia T., Espenel, Cedric, Ponnuswami, Anitha, Ni, Lijun, Woo, Pamelyn J., Taylor, Kathryn R., Agarwal, Amit, Regev, Aviv, Brang, David, Vogel, Hannes, Hervey-Jumper, Shawn, Bergles, Dwight E., Suvà, Mario L., Malenka, Robert C., Monje, Michelle
Published 2020

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

by Wang, Xiuxing, Yang, Kailin, Xie, Qi, Wu, Qiulian, Mack, Stephen C, Kim, Leo J Y, Prager, Briana C, Flavahan, William A, Liu, Xiaojing, Singer, Meromit, Hubert, Christopher G, Miller, Tyler E, Zhou, Wenchao, Huang, Zhi, Fang, Xiaoguang, Suvà, Mario L, Hwang, Tae Hyun, Locasale, Jason W, Bao, Shideng, Rich, Jeremy N, Regev, Aviv, Shi, Yu, Ph. D. Massachusetts Institute of Technology
Published 2018

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

by Suvà, Mario L, Rheinbay, Esther, Gillespie, Shawn M, Patel, Anoop P, Wakimoto, Hiroaki, Rabkin, Samuel D, Riggi, Nicolo, Chi, Andrew S, Cahill, Daniel P, Nahed, Brian V, Curry, William T, Martuza, Robert L, Rivera, Miguel N, Rossetti, Nikki, Kasif, Simon, Beik, Samantha, Kadri, Sabah, Tirosh, Itay, Wortman, Ivo, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Louis, David N, Bernstein, Bradley E
Published 2017

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

by Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alexander K, Bandopadhayay, Pratiti, Beroukhim, Rameen
Published 2020

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

by Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Brastianos, Priscilla K., Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Suvà, Mario L., Dionne, Danielle, Golub, Todd, Getz, Gad Asher, Regev, Aviv, Bernstein, Bradley E.
Published 2018

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

by Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Suvà, Mario L., Golub, Todd, Regev, Aviv
Published 2018

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

by Keskin, Derin B., Anandappa, Annabelle J., Sun, Jing, Tirosh, Itay, Mathewson, Nathan D., Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet A., Hu, Zhuting, Li, Letitia, Le, Phuong M., Allesøe, Rosa L., Richman, Alyssa R., Kowalczyk, Monika S., Abdelrahman, Sara, Geduldig, Jack E., Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J. Bryan, Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars R., Stevens, Jonathan, Lane, William J., Salazar, Andres M., Daley, Heather, Wen, Patrick Y., Chiocca, E. Antonio, Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Getz, Gad Asher, Lander, Eric Steven, Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott J., Ligon, Keith L., Suvà, Mario L., Wucherpfennig, Kai W., Hacohen, Nir, Fritsch, Edward F., Livak, Kenneth J., Ott, Patrick A., Wu, Catherine J., Reardon, David A.
Published 2020

Resolving medulloblastoma cellular architecture by single-cell genomics

by Hovestadt, Volker, Smith, Kyle S., Bihannic, Laure, Filbin, Mariella G., Shaw, McKenzie L., Baumgartner, Alicia, DeWitt, John C., Groves, Andrew, Mayr, Lisa, Weisman, Hannah R., Richman, Alyssa R., Shore, Marni E., Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert A., Phoenix, Timothy N., Hadley, Jennifer L., Tong, Yiai, Houston, Jim, Ashmun, Richard A., DeCuypere, Michael, Sharma, Tanvi, Flasch, Diane, Silkov, Antonina, Ligon, Keith L., Pomeroy, Scott L., Rivera, Miguel N, Rozenblatt-Rosen, Orit, Rusert, Jessica M., Wechsler-Reya, Robert J., Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan M., Gajjar, Amar, Regev, Aviv, Orr, Brent A., Slavc, Irene, Robinson, Giles W., Bernstein, Bradley E., Suvà, Mario L., Northcott, Paul A.
Published 2020