One-Week Exposure to a Free-Choice High-Fat High-Sugar Diet Does Not Interfere With the Lipopolysaccharide-Induced Acute Phase Response in the Hypothalamus of Male Rats

by Evita Belegri, Evita Belegri, Leslie Eggels, Leslie Eggels, Leslie Eggels, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur, Anita Boelen, Anita Boelen
Published 2018-04-01

Glucose-Sensing in the Reward System

by Laura L. Koekkoek, Laura L. Koekkoek, Laura L. Koekkoek, Joram D. Mul, Joram D. Mul, Joram D. Mul, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur
Published 2017-12-01

Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers

by Evita Belegri, Merel Rijnsburger, Leslie Eggels, Unga Unmehopa, Wiep Scheper, Anita Boelen, Susanne E. la Fleur, Susanne E. la Fleur
Published 2017-05-01

Daily Gene Expression Rhythms in Rat White Adipose Tissue Do Not Differ Between Subcutaneous and Intra-Abdominal Depots

by Rianne van der Spek, Eric Fliers, Susanne E. la Fleur, Andries Kalsbeek, Andries Kalsbeek
Published 2018-04-01

A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats

by Aurea Susana Blancas-Velazquez, Aurea Susana Blancas-Velazquez, Aurea Susana Blancas-Velazquez, Aurea Susana Blancas-Velazquez, Unga A. Unmehopa, Unga A. Unmehopa, Leslie Eggels, Leslie Eggels, Laura Koekkoek, Laura Koekkoek, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek, Jorge Mendoza, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur
Published 2018-04-01

The Role of the Gut Microbiota in the Gut–Brain Axis in Obesity: Mechanisms and Future Implications

by Jamie van Son, Laura L. Koekkoek, Susanne E. La Fleur, Mireille J. Serlie, Max Nieuwdorp
Published 2021-03-01

Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet.

by José K van den Heuvel, Leslie Eggels, Eric Fliers, Andries Kalsbeek, Roger A H Adan, Susanne E la Fleur
Published 2014-01-01

Differential effects of diet composition and timing of feeding behavior on rat brown adipose tissue and skeletal muscle peripheral clocks

by Paul de Goede, Satish Sen, Johanneke E. Oosterman, Ewout Foppen, Remi Jansen, Susanne E. la Fleur, Etienne Challet, Andries Kalsbeek
Published 2018-01-01

Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner

by Irina V. Milanova, Irina V. Milanova, Martin J. T. Kalsbeek, Martin J. T. Kalsbeek, Xiao-Lan Wang, Xiao-Lan Wang, Nikita L. Korpel, Nikita L. Korpel, Dirk Jan Stenvers, Dirk Jan Stenvers, Samantha E. C. Wolff, Samantha E. C. Wolff, Paul de Goede, Paul de Goede, Annemieke C. Heijboer, Annemieke C. Heijboer, Eric Fliers, Eric Fliers, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur, Andries Kalsbeek, Andries Kalsbeek, Andries Kalsbeek, Chun-Xia Yi, Chun-Xia Yi
Published 2019-06-01

Decreased serotonin transporter immunoreactivity in the human hypothalamic infundibular nucleus of overweight subjects

by Anke eBorgers, Karin eKoopman, Peter eBisschop, Mireille eSerlie, Dick eSwaab, Eric eFliers, Susanne E La Fleur, Anneke eAlkemade
Published 2014-05-01

Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation

by Judith M. van der Harg, Leslie Eggels, Fabian N. Bangel, Silvie R. Ruigrok, Rob Zwart, Jeroen J.M. Hoozemans, Susanne E. la Fleur, Wiep Scheper
Published 2017-07-01

Inhibitory effect of the melanocortin receptor agonist melanotan-II (MTII) on feeding depends on dietary fat content and not obesity in rats on free-choice diets

by José eVan Den Heuvel, Leslie eEggels, Andrea evan Rozen, Eric eFliers, Andries eKalsbeek, Andries eKalsbeek, Roger eAdan, Susanne E la Fleur
Published 2015-12-01

AAV-mediated gene transfer of the obesity-associated gene Etv5 in rat midbrain does not affect energy balance or motivated behavior.

by Arjen J Boender, Nivard A Koning, José K van den Heuvel, Mieneke C M Luijendijk, Andrea J van Rozen, Susanne E la Fleur, Roger A H Adan
Published 2014-01-01

Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson’s disease

by Nicolette M Lammers, Brigitte M Sondermeijer, Marcel eTwickler, Rob M de Bie, Mariëtte T Ackermans, Eric eFliers, P. Richard Schuurman, Susanne E La Fleur, Mireille J Serlie
Published 2014-05-01

The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia

by Martin J.T. Kalsbeek, Samantha E.C. Wolff, Nikita L. Korpel, Susanne E. la Fleur, Johannes A. Romijn, Eric Fliers, Andries Kalsbeek, Dick F. Swaab, Inge Huitinga, Elly M. Hol, Chun-Xia Yi
Published 2020-08-01

Neuroinflammation is not a prerequisite for diabetes-induced tau phosphorylation

by Judith M Van Der Harg, Judith M Van Der Harg, Leslie eEggels, Silvie R Ruigrok, Jeroen JM Hoozemans, Susanne E la Fleur, Wiep eScheper, Wiep eScheper, Wiep eScheper
Published 2015-11-01

Central melanocortins regulate the motivation for sucrose reward.

by Rahul Pandit, Esther M van der Zwaal, Mieneke C M Luijendijk, Maike A D Brans, Andrea J van Rozen, Ralph J A Oude Ophuis, Louk J M J Vanderschuren, Roger A H Adan, Susanne E la Fleur
Published 2015-01-01

Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans

by Kasper W. ter Horst, Pim W. Gilijamse, Ruth I. Versteeg, Mariette T. Ackermans, Aart J. Nederveen, Susanne E. la Fleur, Johannes A. Romijn, Max Nieuwdorp, Dongyan Zhang, Varman T. Samuel, Daniel F. Vatner, Kitt F. Petersen, Gerald I. Shulman, Mireille J. Serlie
Published 2017-06-01

Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat.

by Joram D Mul, Susanne E la Fleur, Pim W Toonen, Anthonieke Afrasiab-Middelman, Rob Binnekade, Dustin Schetters, Michel M M Verheij, Robert M Sears, Judith R Homberg, Anton N M Schoffelmeer, Roger A H Adan, Ralph J DiLeone, Taco J De Vries, Edwin Cuppen
Published 2011-05-01

Alterations in blood glucose and plasma glucagon concentrations during deep brain stimulation in the shell region of the nucleus accumbens in rats

by Charlene eDiepenbroek, Geoffrey evan der Plasse, Geoffrey evan der Plasse, Leslie eEggels, Merel eRijnsburger, Matthijs eFeenstra, Matthijs eFeenstra, Andries eKalsbeek, Andries eKalsbeek, Damiaan eDenys, Damiaan eDenys, Eric eFliers, Mireille J Serlie, Susanne E la Fleur
Published 2013-12-01