The genomic landscape of chronic lymphocytic leukaemia: biological and clinical implications

by Strefford, Jonathan C.
Published 2015

Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy

by Sinclair, Paul B., Parker, Helen, An, Qian, Rand, Vikki, Ensor, Hannah, Harrison, Christine J., Strefford, Jonathan C.
Published 2011

The outcome of chronic lymphocytic leukaemia patients with 97% IGHV gene identity to germline is distinct from cases with

by Davis, Zadie, Forconi, Francesco, Parker, Anton, Gardiner, Anne, Thomas, Peter, Catovsky, Daniel, Rose-Zerilli, Matthew, Strefford, Jonathan, Oscier, David
Published 2016

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma

by Parry, Marina, Rose-Zerilli, Matthew J. J., Gibson, Jane, Ennis, Sarah, Walewska, Renata, Forster, Jade, Parker, Helen, Davis, Zadie, Gardiner, Anne, Collins, Andrew, Oscier, David G., Strefford, Jonathan C.
Published 2013

Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia

by Rand, Vikki, Parker, Helen, Russell, Lisa J, Schwab, Claire, Ensor, Hannah, Irving, Julie, Jones, Lisa, Masic, Dino, Minto, Lynne, Morrison, Heather, Ryan, Sarra, Robinson, Hazel, Sinclair, Paul, Moorman, Anthony V, Strefford, Jonathan C., Harrison, Christine J.
Published 2011

ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial

by Rose-Zerilli, Matthew J., Forster, Jade, Parker, Helen, Parker, Anton, Rodríguez, Ana E., Chaplin, Tracy, Gardiner, Anne, Steele, Andrew J., Collins, A., Young, Bryan D., Skowronska, Anna, Catovsky, Daniel, Stankovic, Tanja, Oscier, D.G, Strefford, Jonathan C.
Published 2014

Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease

by Rose-Zerilli, Matthew, Gibson, Jane, Wang, Jun, Tapper, Wi, Davis, Zadie, Parker, Helen, Larrayoz, Marta, McCarthy, Helen, Walewska, Renata, Forster, Jade, Gardiner, Anne, Steele, Andrew, Chelala, Claude, Ennis, Sarah, Collins, Andrew, Oakes, Christopher, Oscier, David, Strefford, Jonathan
Published 2016

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the E?-TCL1 mouse model

by Blunt, Matthew D., Carter, Matthew J., Larrayoz, Marta, Smith, Lindsay D., Aguilar-Hernandez, Maria, Cox, Kerry L., Tipton, Thomas R.W, Reynolds, Mark, Murphy, Sarah, Lemm, Elizabeth, Dias, Samantha, Duncombe, Andrew S., Strefford, Jonathan C., Johnson, Peter W.M, Forconi, Francesco, Stevenson, Freda K., Packham, Graham, Cragg, Mark S., Steele, Andrew J.
Published 2015

Genetics and prognostication in splenic marginal zone lymphoma: revelations from deep sequencing

by Parry, Marina, Rose-Zerilli, Matthew J., Ljungstrom, Viktor, Gibson, Jane, Wang, Jun, Walewska, Renata, Parker, Helen, Parker, A, David, Zadie, Gardiner, Anne, McIver-Brown, Neil, Kalpadakis, Christina, Xochelli, Aliki, Anagnostopoulos, Achilles, Fazi, Claudia, Gonzalez de Castro, David, Dearden, Claire, Pratt, Guy, Rosenquist, Richard, Ashton-Key, Margaret, Forconi, Francesco, Collins, Andrew R., Ghia, Paolo, Matutes, Estella, Pangalis, Gerassimos, Stamatopoulos, Kostas, Oscier, David G., Strefford, Jonathan C.
Published 2015