Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

by Sushama Telwatte, Sara Morón-López, Dvir Aran, Peggy Kim, Christine Hsieh, Sunil Joshi, Mauricio Montano, Warner C. Greene, Atul J. Butte, Joseph K. Wong, Steven A. Yukl
Published 2019-11-01

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.

by Sushama Telwatte, Sulggi Lee, Ma Somsouk, Hiroyu Hatano, Christopher Baker, Philipp Kaiser, Peggy Kim, Tsui-Hua Chen, Jeffrey Milush, Peter W Hunt, Steven G Deeks, Joseph K Wong, Steven A Yukl
Published 2018-11-01

Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults.

by Steven A Yukl, Amandeep K Shergill, Valerie Girling, Qingsheng Li, Maudi Killian, Lorrie Epling, Peilin Li, Philipp Kaiser, Ashley Haase, Diane V Havlir, Kenneth McQuaid, Elizabeth Sinclair, Joseph K Wong
Published 2015-01-01

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.

by Sulggi A Lee, Peter Bacchetti, Nicolas Chomont, Remi Fromentin, Sharon R Lewin, Una O'Doherty, Sarah Palmer, Douglas D Richman, Janet D Siliciano, Steven A Yukl, Steven G Deeks, Peter D Burbelo
Published 2016-01-01

CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells.

by Leslie R Cockerham, Janet D Siliciano, Elizabeth Sinclair, Una O'Doherty, Sarah Palmer, Steven A Yukl, Matt C Strain, Nicolas Chomont, Frederick M Hecht, Robert F Siliciano, Douglas D Richman, Steven G Deeks
Published 2014-01-01

Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.

by Sara Moron-Lopez, Sushama Telwatte, Indra Sarabia, Emilie Battivelli, Mauricio Montano, Amanda B Macedo, Dvir Aran, Atul J Butte, R Brad Jones, Alberto Bosque, Eric Verdin, Warner C Greene, Joseph K Wong, Steven A Yukl
Published 2020-11-01

Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.

by Feng Hsiao, Julie Frouard, Andrea Gramatica, Guorui Xie, Sushama Telwatte, Guinevere Q Lee, Pavitra Roychoudhury, Roland Schwarzer, Xiaoyu Luo, Steven A Yukl, Sulggi Lee, Rebecca Hoh, Steven G Deeks, R Brad Jones, Marielle Cavrois, Warner C Greene, Nadia R Roan
Published 2020-04-01

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

by Leslie Renee Cockerham, Steven A. Yukl, Kara Harvill, Ma Somsouk, Sunil K. Joshi, Elizabeth Sinclair, Teri Liegler, Rebecca Hoh, Sophie Lyons, Peter W. Hunt, Adam Rupert, Irini Sereti, David R. Morcock, Ajantha Rhodes, Claire Emson, Marc K. Hellerstein, Jacob D. Estes, Sharon Lewin, Steven G. Deeks, Hiroyu Hatano
Published 2017-08-01

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

by Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Feng Hsiao, Tongcui Ma, Vincent Morcilla, Ashley Lee, Sushama Telwatte, Reuben Thomas, Whitney Tamaki, Benjamin Wheeler, Rebecca Hoh, Ma Somsouk, Poonam Vohra, Jeffrey Milush, Katherine Sholtis James, Nancie M Archin, Peter W Hunt, Steven G Deeks, Steven A Yukl, Sarah Palmer, Warner C Greene, Nadia R Roan
Published 2020-09-01

Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.

by Hiroyu Hatano, Steven A Yukl, April L Ferre, Erin H Graf, Ma Somsouk, Elizabeth Sinclair, Mohamed Abdel-Mohsen, Teri Liegler, Kara Harvill, Rebecca Hoh, Sarah Palmer, Peter Bacchetti, Peter W Hunt, Jeffrey N Martin, Joseph M McCune, Russell P Tracy, Michael P Busch, Una O'Doherty, Barbara L Shacklett, Joseph K Wong, Steven G Deeks
Published 2013-01-01

Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.

by Susanne Eriksson, Erin H Graf, Viktor Dahl, Matthew C Strain, Steven A Yukl, Elena S Lysenko, Ronald J Bosch, Jun Lai, Stanley Chioma, Fatemeh Emad, Mohamed Abdel-Mohsen, Rebecca Hoh, Frederick Hecht, Peter Hunt, Ma Somsouk, Joseph Wong, Rowena Johnston, Robert F Siliciano, Douglas D Richman, Una O'Doherty, Sarah Palmer, Steven G Deeks, Janet D Siliciano
Published 2013-02-01

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.

by Charline Bacchus-Souffan, Mark Fitch, Jori Symons, Mohamed Abdel-Mohsen, Daniel B Reeves, Rebecca Hoh, Mars Stone, Joseph Hiatt, Peggy Kim, Abha Chopra, Haelee Ahn, Vanessa A York, Daniel L Cameron, Frederick M Hecht, Jeffrey N Martin, Steven A Yukl, Simon Mallal, Paul U Cameron, Steven G Deeks, Joshua T Schiffer, Sharon R Lewin, Marc K Hellerstein, Joseph M McCune, Peter W Hunt
Published 2021-01-01

Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient.

by Steven A Yukl, Eli Boritz, Michael Busch, Christopher Bentsen, Tae-Wook Chun, Daniel Douek, Evelyn Eisele, Ashley Haase, Ya-Chi Ho, Gero Hütter, J Shawn Justement, Sheila Keating, Tzong-Hae Lee, Peilin Li, Danielle Murray, Sarah Palmer, Christopher Pilcher, Satish Pillai, Richard W Price, Meghan Rothenberger, Timothy Schacker, Janet Siliciano, Robert Siliciano, Elizabeth Sinclair, Matt Strain, Joseph Wong, Douglas Richman, Steven G Deeks
Published 2013-01-01

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

by Timothy J Henrich, Hiroyu Hatano, Oliver Bacon, Louise E Hogan, Rachel Rutishauser, Alison Hill, Mary F Kearney, Elizabeth M Anderson, Susan P Buchbinder, Stephanie E Cohen, Mohamed Abdel-Mohsen, Christopher W Pohlmeyer, Remi Fromentin, Rebecca Hoh, Albert Y Liu, Joseph M McCune, Jonathan Spindler, Kelly Metcalf-Pate, Kristen S Hobbs, Cassandra Thanh, Erica A Gibson, Daniel R Kuritzkes, Robert F Siliciano, Richard W Price, Douglas D Richman, Nicolas Chomont, Janet D Siliciano, John W Mellors, Steven A Yukl, Joel N Blankson, Teri Liegler, Steven G Deeks
Published 2017-11-01