Reversing the Negative Genomic Effects of Aging with Short-Term Calorie Restriction

by Stephen R. Spindler
Published 2001-01-01

Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila.

by Stephen R Spindler, Rui Li, Joseph M Dhahbi, Amy Yamakawa, Frank Sauer
Published 2012-01-01

Deep sequencing reveals novel microRNAs and regulation of microRNA expression during cell senescence.

by Joseph M Dhahbi, Hani Atamna, Dario Boffelli, Wendy Magis, Stephen R Spindler, David I K Martin
Published 2011-01-01

Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation.

by Stephen R Spindler, Rui Li, Joseph M Dhahbi, Amy Yamakawa, Patricia Mote, Rolf Bodmer, Karen Ocorr, Renee T Williams, Yinsheng Wang, Kenneth P Ablao
Published 2012-01-01

Delayed and accelerated aging share common longevity assurance mechanisms.

by Björn Schumacher, Ingrid van der Pluijm, Michael J Moorhouse, Theodore Kosteas, Andria Rasile Robinson, Yousin Suh, Timo M Breit, Harry van Steeg, Laura J Niedernhofer, Wilfred van Ijcken, Andrzej Bartke, Stephen R Spindler, Jan H J Hoeijmakers, Gijsbertus T J van der Horst, George A Garinis
Published 2008-08-01