AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles

by Jørgen Jensen, Stephen O'Rahilly
Published 2017-04-01

Fat: an evolving issue

by John R. Speakman, Stephen O’Rahilly
Published 2012-09-01

Development, factor structure and application of the Dog Obesity Risk and Appetite (DORA) questionnaire

by Eleanor Raffan, Stephen P. Smith, Stephen O’Rahilly, Jane Wardle
Published 2015-09-01

The McKittrick–Wheelock syndrome: a rare cause of curable diabetes

by Benjamin G Challis, Chung Thong Lim, Alison Cluroe, Ewen Cameron, Stephen O’Rahilly
Published 2016-05-01

Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity.

by Karla P Figueroa, Sadaf Farooqi, Kristopher Harrup, Johnathan Frank, Stephen O'Rahilly, Stefan M Pulst
Published 2009-12-01

Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm

by Pawan Gulati, Edward Avezov, Marcella Ma, Robin Antrobus, Paul Lehner, Stephen O’Rahilly, Giles S. H. Yeo
Published 2014-10-01

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

by Md. Mesbah Uddin Talukder, M.F. Michelle Sim, Stephen O'Rahilly, J. Michael Edwardson, Justin J. Rochford
Published 2015-03-01

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

by Yi-Chun Loraine Tung, Eduard Ayuso, Xiaoye Shan, Fatima Bosch, Stephen O'Rahilly, Anthony P Coll, Giles S H Yeo
Published 2010-01-01

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.

by Inês Barroso, Jian'an Luan, Rita P S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, D Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham
Published 2003-10-01

In PLoS Biology, volume 1, issue 1:: Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.

by Inês Barroso, Jian'an Luan, Rita P. S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, David Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham
Published 2003-12-01

FTO is necessary for the induction of leptin resistance by high-fat feeding

by Y.C. Loraine Tung, Pawan Gulati, Che-Hsiung Liu, Debra Rimmington, Rowena Dennis, Marcella Ma, Vladimir Saudek, Stephen O'Rahilly, Anthony P. Coll, Giles S.H. Yeo
Published 2015-04-01

Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels

by Sumit Bhattacharyya, Jian'an Luan, Benjamin Challis, Julia Keogh, Carl Montague, John Brennand, John Morten, Sarah Lowenbeim, Suzanne Jenkins, I. Sadaf Farooqi, Nicholas J. Wareham, Stephen O'Rahilly
Published 2006-04-01

Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

by Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi
Published 2016-10-01

Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion

by Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J. Conway, Marcella K.L. Ma, Davide Chiarugi, Vladimir Saudek, Stephen O’Rahilly, David B. Savage
Published 2021-03-01

Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

by Peter Kirwan, Richard G. Kay, Bas Brouwers, Vicente Herranz-Pérez, Magdalena Jura, Pierre Larraufie, Julie Jerber, Jason Pembroke, Theresa Bartels, Anne White, Fiona M. Gribble, Frank Reimann, I. Sadaf Farooqi, Stephen O'Rahilly, Florian T. Merkle
Published 2018-11-01

Genetic architecture of human thinness compared to severe obesity.

by Fernando Riveros-McKay, Vanisha Mistry, Rebecca Bounds, Audrey Hendricks, Julia M Keogh, Hannah Thomas, Elana Henning, Laura J Corbin, Understanding Society Scientific Group, Stephen O'Rahilly, Eleftheria Zeggini, Eleanor Wheeler, Inês Barroso, I Sadaf Farooqi
Published 2019-01-01

Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study [version 1; referees: 2 approve...

by Clive J. Petry, Ken K. Ong, Keith A. Burling, Peter Barker, Sandra F. Goodburn, John R.B. Perry, Carlo L. Acerini, Ieuan A. Hughes, Rebecca C. Painter, Gijs B. Afink, David B. Dunger, Stephen O'Rahilly
Published 2018-09-01

Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

by Ming Yang, Tamana Darwish, Pierre Larraufie, Debra Rimmington, Irene Cimino, Deborah A. Goldspink, Benjamin Jenkins, Albert Koulman, Cheryl A. Brighton, Marcella Ma, Brian Y. H. Lam, Anthony P. Coll, Stephen O’Rahilly, Frank Reimann, Fiona M. Gribble
Published 2021-01-01

Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.

by Fiona McMurray, Chris D Church, Rachel Larder, George Nicholson, Sara Wells, Lydia Teboul, Y C Loraine Tung, Debra Rimmington, Fatima Bosch, Veronica Jimenez, Giles S H Yeo, Stephen O'Rahilly, Frances M Ashcroft, Anthony P Coll, Roger D Cox
Published 2013-01-01

Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure

by Albert Kwok, Ilona Zvetkova, Sam Virtue, Ineke Luijten, Isabel Huang-Doran, Patsy Tomlinson, David A. Bulger, James West, Steven Murfitt, Julian Griffin, Rafeah Alam, Daniel Hart, Rachel Knox, Peter Voshol, Antonio Vidal-Puig, Jørgen Jensen, Stephen O'Rahilly, Robert K. Semple
Published 2020-10-01