Unique Biology and Single-Channel Properties of GluN2A- and GluN2C-Containing Triheteromeric N-Methyl-D-Aspartate Receptors

by Subhrajit Bhattacharya , Stephen F Traynelis
Published 2018-11-01

Corrigendum to “Human GRIN2B variants in neurodevelopmental disorders” [J Pharmacol Sci 132 (2) 115–121]

by Chun Hu, Wenjuan Chen, Scott J. Myers, Hongjie Yuan, Stephen F. Traynelis
Published 2017-04-01

Human GRIN2B variants in neurodevelopmental disorders

by Chun Hu, Wenjuan Chen, Scott J. Myers, Hongjie Yuan, Stephen F. Traynelis
Published 2016-10-01

Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease

by Stefka Gyoneva, Lauren Shapiro, Carlos Lazo, Ethel Garnier-Amblard, Yoland Smith, Gary W. Miller, Stephen F. Traynelis
Published 2014-07-01

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions [version 1; peer review: 2 approved]

by Scott J Myers, Hongjie Yuan, Jing-Qiong Kang, Francis Chee Kuan Tan, Stephen F Traynelis, Chian-Ming Low
Published 2019-11-01

Randomized, Placebo-Controlled, Double-Blind Pilot Study of D-Cycloserine in Chronic Stroke

by Andrew J. Butler, Justiss Kallos, Stephen N. Housley, Michelle C. LaPlaca, Stephen F. Traynelis, Steven L. Wolf
Published 2015-01-01

Recurrent seizure‐related GRIN1 variant: Molecular mechanism and targeted therapy

by Yuchen Xu, Rui Song, Wenjuan Chen, Katie Strong, Daniel Shrey, Satyanarayana Gedela, Stephen F. Traynelis, Guojun Zhang, Hongjie Yuan
Published 2021-07-01

Glutamatergic Tuning of Hyperactive Striatal Projection Neurons Controls the Motor Response to Dopamine Replacement in Parkinsonian Primates

by Arun Singh, Meagan A. Jenkins, Kenneth J. Burke, Jr., Goichi Beck, Andrew Jenkins, Annalisa Scimemi, Stephen F. Traynelis, Stella M. Papa
Published 2018-01-01

Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

by Michael C. Regan, Zongjian Zhu, Hongjie Yuan, Scott J. Myers, Dave S. Menaldino, Yesim A. Tahirovic, Dennis C. Liotta, Stephen F. Traynelis, Hiro Furukawa
Published 2019-01-01

A de novo GRIN1 Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology

by Jin Zhang, Weiting Tang, Nidhi K. Bhatia, Yuchen Xu, Yuchen Xu, Nabina Paudyal, Ding Liu, Sukhan Kim, Sukhan Kim, Rui Song, Rui Song, Wenshu XiangWei, Gil Shaulsky, Scott J. Myers, Scott J. Myers, William Dobyns, Vasanthi Jayaraman, Stephen F. Traynelis, Stephen F. Traynelis, Hongjie Yuan, Hongjie Yuan, Xiuhua Bozarth, Xiuhua Bozarth
Published 2021-08-01

A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia.

by Kai Gao, Anel Tankovic, Yujia Zhang, Hirofumi Kusumoto, Jin Zhang, Wenjuan Chen, Wenshu XiangWei, Gil H Shaulsky, Chun Hu, Stephen F Traynelis, Hongjie Yuan, Yuwu Jiang
Published 2017-01-01

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

by Riley Perszyk, Brooke M Katzman, Hirofumi Kusumoto, Steven A Kell, Matthew P Epplin, Yesim A Tahirovic, Rhonda L Moore, David Menaldino, Pieter Burger, Dennis C Liotta, Stephen F Traynelis
Published 2018-05-01

Correction to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors

by Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M. Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F. Traynelis, Yong Chul Bae, Se-Young Choi, C. Justin Lee
Published 2021-06-01

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.

by Kevin K Ogden, Wenjuan Chen, Sharon A Swanger, Miranda J McDaniel, Linlin Z Fan, Chun Hu, Anel Tankovic, Hirofumi Kusumoto, Gabrielle J Kosobucki, Anthony J Schulien, Zhuocheng Su, Joseph Pecha, Subhrajit Bhattacharya, Slavé Petrovski, Adam E Cohen, Elias Aizenman, Stephen F Traynelis, Hongjie Yuan
Published 2017-01-01