MDM2 Antagonists Induce a Paradoxical Activation of Erk1/2 through a P53-Dependent Mechanism in Dedifferentiated Liposarcomas: Implications for Combinatorial Strategies

by Shomereeta Roy, Audrey Laroche-Clary, Stephanie Verbeke, Marie-Alix Derieppe, Antoine Italiano
Published 2020-08-01

High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapie...

by Maud Toulmonde, Carlo Lucchesi, Stéphanie Verbeke, Amandine Crombe, Julien Adam, Damien Geneste, Vanessa Chaire, Audrey Laroche-Clary, Raul Perret, François Bertucci, Frederic Bertolo, Laurence Bianchini, Bérengère Dadone-Montaudie, Todd Hembrough, Steve Sweet, Yeoun Jin Kim, Fabiola Cecchi, François Le Loarer, Antoine Italiano
Published 2020-12-01