Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production.

by Sha Tang, Phung Khanh Le, Stephanie Tse, Douglas C Wallace, Taosheng Huang
Published 2009-01-01

Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner.

by Parvin Shahrestani, Hung-Tat Leung, Phung Khanh Le, William L Pak, Stephanie Tse, Karen Ocorr, Taosheng Huang
Published 2009-08-01

The molecular mechanisms of OPA1-mediated optic atrophy in Drosophila model and prospects for antioxidant treatment.

by Will Yarosh, Jessica Monserrate, James Jiayuan Tong, Stephanie Tse, Phung Khanh Le, Kimberly Nguyen, Carrie B Brachmann, Douglas C Wallace, Taosheng Huang
Published 2008-01-01