Proteolytic α-Synuclein Cleavage in Health and Disease

by Alexandra Bluhm, Sarah Schrempel, Stephan von Hörsten, Anja Schulze, Steffen Roßner
Published 2021-05-01

Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy

by Lisa Mészáros, Markus J. Riemenschneider, Heiko Gassner, Franz Marxreiter, Stephan von Hörsten, Alana Hoffmann, Jürgen Winkler
Published 2021-04-01

Thirty Mouse Strain Survey of Voluntary Physical Activity and Energy Expenditure: Influence of Strain, Sex and Day–Night Variation

by Christine König, Anne-Christine Plank, Alexander Kapp, Ivanna K. Timotius, Ivanna K. Timotius, Stephan von Hörsten, Katharina Zimmermann
Published 2020-07-01

Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington's disease

by Benjamin R. Miller, Adam G. Walker, Stephen C. Fowler, Stephan von Hörsten, Olaf Riess, Michael A. Johnson, George V. Rebec
Published 2010-01-01

Altered hypothalamic protein expression in a rat model of Huntington's disease.

by Wei-na Cong, Huan Cai, Rui Wang, Caitlin M Daimon, Stuart Maudsley, Kerstin Raber, Fabio Canneva, Stephan von Hörsten, Bronwen Martin
Published 2012-01-01

Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease

by Wei-na Cong, Huan Cai, Rui Wang, Caitlin M. Daimon, Stuart Maudsley, Kerstin Raber, Fabio Canneva, Stephan von Hörsten, Bronwen Martin
Published 2012-01-01

Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease.

by Wei-na Cong, Huan Cai, Rui Wang, Caitlin M. Daimon, Stuart Maudsley, Kerstin Raber, Fabio Canneva, Stephan von Hörsten, Bronwen Martin
Published 2012-01-01

Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5

by Anne-Christine Plank, Stefan Frey, Lukas Andreas Basedow, Jalal Solati, Fabio Canneva, Stephan von Hörsten, Oliver Kratz, Gunther H. Moll, Yulia Golub
Published 2021-03-01

Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

by Anja Schulze-Krebs, Fabio Canneva, Judith Stemick, Anne-Christine Plank, Julia Harrer, Gillian P. Bates, Daniel Aeschlimann, Joan S. Steffan, Stephan von Hörsten
Published 2021-08-01

Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis

by Ivanna K. Timotius, Fabio Canneva, Georgia Minakaki, Cristian Pasluosta, Sandra Moceri, Nicolas Casadei, Olaf Riess, Jürgen Winkler, Jochen Klucken, Stephan von Hörsten, Bjoern Eskofier
Published 2018-04-01

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

by Rinske Vlamings, Abdelhamid Benazzouz, Jonathan Chetrit, Marcus L.F. Janssen, Ramazan Kozan, Veerle Visser-Vandewalle, Harry W.M. Steinbusch, Stephan von Hörsten, Yasin Temel
Published 2012-12-01

Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheime...

by Maike Hartlage-Rübsamen, Veronika Ratz, Ulrike Zeitschel, Lukas Finzel, Lisa Machner, Janett Köppen, Anja Schulze, Hans-Ulrich Demuth, Stephan von Hörsten, Corinna Höfling, Steffen Roßner
Published 2019-05-01

Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats

by Taygun C. Uzuneser, Jil Speidel, Georgios Kogias, An-Li Wang, Maria A. de Souza Silva, Joseph P. Huston, Iulia Zoicas, Stephan von Hörsten, Johannes Kornhuber, Carsten Korth, Christian P. Müller
Published 2019-04-01

Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts.

by Mahesh Kandasamy, Michael Rosskopf, Katrin Wagner, Barbara Klein, Sebastien Couillard-Despres, Herbert A Reitsamer, Michael Stephan, Huu Phuc Nguyen, Olaf Riess, Ulrich Bogdahn, Jürgen Winkler, Stephan von Hörsten, Ludwig Aigner
Published 2015-01-01

Impaired decision making and loss of inhibitory-control in a rat model of Huntington disease

by Nicole El Massioui, Charlotte Lamirault, Sara Yagüe, Najia Adjeroud, Daniel Garces, Alexis Maillard, Lucille Tallot, Libo Yu-Taeger, Olaf Riess, Philippe Allain, Huu Phuc Nguyen, Stephan Von Hörsten, Valérie Doyère
Published 2016-10-01

Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats

by Johanna Habermeyer, Janina Boyken, Julia Harrer, Fabio Canneva, Veronika Ratz, Sandra Moceri, Jakob Admard, Nicolas Casadei, Gregor Jost, Tobias Bäuerle, Thomas Frenzel, Christoph Schmitz, Gunnar Schütz, Hubertus Pietsch, Stephan von Hörsten
Published 2020-12-01

Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease

by Anne-Christine Plank, Fabio Canneva, Kerstin A. Raber, Yvonne K. Urbach, Julia Dobner, Maja Puchades, Jan G. Bjaalie, Clarissa Gillmann, Tobias Bäuerle, Olaf Riess, Hoa H. P. Nguyen, Stephan von Hörsten
Published 2018-01-01

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

by Janett Köppen, Anja Schulze, Lisa Machner, Michael Wermann, Rico Eichentopf, Max Guthardt, Angelika Hähnel, Jessica Klehm, Marie-Christin Kriegeskorte, Maike Hartlage-Rübsamen, Markus Morawski, Stephan von Hörsten, Hans-Ulrich Demuth, Steffen Roßner, Stephan Schilling
Published 2020-01-01

The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells

by Kim Le Cann, Alec Foerster, Corinna Rösseler, Andelain Erickson, Petra Hautvast, Sebastian Giesselmann, Daniel Pensold, Ingo Kurth, Markus Rothermel, Virginia B. Mattis, Geraldine Zimmer-Bensch, Stephan von Hörsten, Bernd Denecke, Tim Clarner, Jannis Meents, Angelika Lampert
Published 2021-03-01

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

by Orsolya Kántor, Yasin Temel, Carsten Holzmann, Kerstin Raber, Huu-Phuc Nguyen, Chunyan Cao, Hatice Özen Türkoglu, Bart P.F. Rutten, Veerle Visser-Vandewalle, Harry W.M. Steinbusch, Arjan Blokland, Hubert Korr, Olaf Riess, Stephan von Hörsten, Christoph Schmitz
Published 2006-06-01