High quality, small molecule-activity datasets for kinase research [version 1; referees: 2 approved]

by Rajan Sharma, Stephan C. Schürer, Steven M. Muskal
Published 2016-06-01

High quality, small molecule-activity datasets for kinase research [version 3; referees: 2 approved]

by Rajan Sharma, Stephan C. Schürer, Steven M. Muskal
Published 2016-10-01

High quality, small molecule-activity datasets for kinase research [version 2; referees: 2 approved]

by Rajan Sharma, Stephan C. Schürer, Steven M. Muskal
Published 2016-07-01

Polypharmacology or Promiscuity? Structural Interactions of Resveratrol With Its Bandwagon of Targets

by Uzma Saqib, Tanya T. Kelley, Siva K. Panguluri, Dongfang Liu, Rajkumar Savai, Mirza S. Baig, Stephan C. Schürer, Stephan C. Schürer
Published 2018-10-01

The Clinical Kinase Index: A Method to Prioritize Understudied Kinases as Drug Targets for the Treatment of Cancer

by Derek Essegian, Rimpi Khurana, Vasileios Stathias, Stephan C. Schürer
Published 2020-10-01

Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends cha...

by Dusica eVidovic, Amar eKoleti, Stephan C Schurer
Published 2014-09-01

Fast and accurate semantic annotation of bioassays exploiting a hybrid of machine learning and user confirmation

by Alex M. Clark, Barry A. Bunin, Nadia K. Litterman, Stephan C. Schürer, Ubbo Visser
Published 2014-08-01

Drug Repositioning in Glioblastoma: A Pathway Perspective

by Sze Kiat Tan, Anna Jermakowicz, Adnan K. Mookhtiar, Charles B. Nemeroff, Stephan C. Schürer, Nagi G. Ayad
Published 2018-03-01

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

by Bryce K. Allen, Saurabh Mehta, Stuart W. J. Ember, Jin-Yi Zhu, Ernst Schönbrunn, Nagi G. Ayad, Stephan C. Schürer
Published 2017-08-01

Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO).

by Uma D Vempati, Magdalena J Przydzial, Caty Chung, Saminda Abeyruwan, Ahsan Mir, Kunie Sakurai, Ubbo Visser, Vance P Lemmon, Stephan C Schürer
Published 2012-01-01

Novel Curcumin Inspired Bis-Chalcone Promotes Endoplasmic Reticulum Stress and Glioblastoma Neurosphere Cell Death

by Lorenzo Sansalone, Eduardo A. Veliz, Nadia G. Myrthil, Vasileios Stathias, Winston Walters, Ingrid I. Torrens, Stephan C. Schürer, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Published 2019-03-01

Drug and disease signature integration identifies synergistic combinations in glioblastoma

by Vasileios Stathias, Anna M. Jermakowicz, Marie E. Maloof, Michele Forlin, Winston Walters, Robert K. Suter, Michael A. Durante, Sion L. Williams, J. William Harbour, Claude-Henry Volmar, Nicholas J. Lyons, Claes Wahlestedt, Regina M. Graham, Michael E. Ivan, Ricardo J. Komotar, Jann N. Sarkaria, Aravind Subramanian, Todd R. Golub, Stephan C. Schürer, Nagi G. Ayad
Published 2018-12-01

Drug target ontology to classify and integrate drug discovery data

by Yu Lin, Saurabh Mehta, Hande Küçük-McGinty, John Paul Turner, Dusica Vidovic, Michele Forlin, Amar Koleti, Dac-Trung Nguyen, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, Caty Chung, Christopher Mader, Ubbo Visser, Jeremy J. Yang, Cristian G. Bologa, Tudor I. Oprea, Stephan C. Schürer
Published 2017-11-01