Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability.

by Stefan Legewie, Nils Blüthgen, Hanspeter Herzel
Published 2006-09-01

Determinants of cell-to-cell variability in protein kinase signaling.

by Matthias Jeschke, Stephan Baumgärtner, Stefan Legewie
Published 2013-01-01

Correction: Multi-Target Regulation by Small RNAs Synchronizes Gene Expression Thresholds and May Enhance Ultrasensitive Behavior

by Jörn Matthias Schmiedel, Ilka Maria Axmann, Stefan Legewie
Published 2013-01-01

Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction.

by Stefan Legewie, Nils Blüthgen, Reinhold Schäfer, Hanspeter Herzel
Published 2005-10-01

Correction: Multi-Target Regulation by Small RNAs Synchronizes Gene Expression Thresholds and May Enhance Ultrasensitive Behavior.

by Jörn Matthias Schmiedel, Ilka Maria Axmann, Stefan Legewie
Published 2013-01-01

Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior.

by Jörn Matthias Schmiedel, Ilka Maria Axmann, Stefan Legewie
Published 2012-01-01

A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis.

by Guillem Casanovas, Anashua Banerji, Flavia d'Alessio, Martina U Muckenthaler, Stefan Legewie
Published 2014-01-01

Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms.

by Mihaela Enculescu, Christoph Metzendorf, Richard Sparla, Maximilian Hahnel, Johannes Bode, Martina U Muckenthaler, Stefan Legewie
Published 2017-01-01

Correlated receptor transport processes buffer single-cell heterogeneity.

by Stefan M Kallenberger, Anne L Unger, Stefan Legewie, Konstantinos Lymperopoulos, Ursula Klingmüller, Roland Eils, Dirk-Peter Herten
Published 2017-09-01

Quantifying post-transcriptional regulation in the development of Drosophila melanogaster

by Kolja Becker, Alina Bluhm, Nuria Casas-Vila, Nadja Dinges, Mario Dejung, Sergi Sayols, Clemens Kreutz, Jean-Yves Roignant, Falk Butter, Stefan Legewie
Published 2018-11-01

Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesis

by Simon Braun, Mihaela Enculescu, Samarth T. Setty, Mariela Cortés-López, Bernardo P. de Almeida, F. X.  Reymond Sutandy, Laura Schulz, Anke Busch, Markus Seiler, Stefanie Ebersberger, Nuno L. Barbosa-Morais, Stefan Legewie, Julian König, Kathi Zarnack
Published 2018-08-01