Application of Optical Biosensors in Small-Molecule Screening Activities

by Wolfgang Knecht, Johan F. Carlsson, Stefan Geschwindner
Published 2012-03-01

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion.

by Krister Bamberg, Ulrika Johansson, Karl Edman, Lena William-Olsson, Susanna Myhre, Anders Gunnarsson, Stefan Geschwindner, Anna Aagaard, Anna Björnson Granqvist, Frédéric Jaisser, Yufeng Huang, Kenneth L Granberg, Rasmus Jansson-Löfmark, Judith Hartleib-Geschwindner
Published 2018-01-01

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

by Amanda J. Kennedy, Linda Sundström, Stefan Geschwindner, Eunice K. Y. Poon, Yuhong Jiang, Rongfeng Chen, Rob Cooke, Shawn Johnstone, Andrew Madin, Junxian Lim, Qingqi Liu, Rink-Jan Lohman, Anneli Nordqvist, Maria Fridén-Saxin, Wenzhen Yang, Dean G. Brown, David P. Fairlie, Niek Dekker
Published 2020-12-01

Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.

by Ola Fjellström, Niklas Larsson, Shin-Ichiro Yasuda, Takuma Tsuchida, Takahiro Oguma, Anna Marley, Charlotte Wennberg-Huldt, Daniel Hovdal, Hajime Fukuda, Yukimi Yoneyama, Kazuyo Sasaki, Anders Johansson, Sara Lundqvist, Johan Brengdahl, Richard J Isaacs, Daniel Brown, Stefan Geschwindner, Lambertus Benthem, Claire Priest, Andrew Turnbull
Published 2015-01-01

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

by Hélène Adihou, Ranganath Gopalakrishnan, Tim Förster, Stéphanie M. Guéret, Raphael Gasper, Stefan Geschwindner, Carmen Carrillo García, Hacer Karatas, Ajaybabu V. Pobbati, Mercedes Vazquez‐Chantada, Paul Davey, Carola M. Wassvik, Jeremy Kah Sheng Pang, Boon Seng Soh, Wanjin Hong, Elisabetta Chiarparin, Dennis Schade, Alleyn T. Plowright, Eric Valeur, Malin Lemurell, Tom N. Grossmann, Herbert Waldmann
Published 2020-10-01