Boosting in planta production of antigens derived from the porcine reproductive and respiratory syndrome virus (PRRSV) and subsequent evaluation of their immunogenicity.

by Robin Piron, Stefaan De Koker, Annelies De Paepe, Julie Goossens, Johan Grooten, Hans Nauwynck, Ann Depicker
Published 2014-01-01

The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration

by Lien Van Hoecke, Kenny Roose, Marlies Ballegeer, Zifu Zhong, Niek N. Sanders, Stefaan De Koker, Xavier Saelens, Sandra Van Lint
Published 2020-12-01

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

by Lien Van Hoecke, Sandra Van Lint, Kenny Roose, Alexander Van Parys, Peter Vandenabeele, Johan Grooten, Jan Tavernier, Stefaan De Koker, Xavier Saelens
Published 2018-08-01

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

by Tania Løve Aaes, Agnieszka Kaczmarek, Tinneke Delvaeye, Bram De Craene, Stefaan De Koker, Liesbeth Heyndrickx, Iris Delrue, Joachim Taminau, Bartosz Wiernicki, Philippe De Groote, Abhishek D. Garg, Luc Leybaert, Johan Grooten, Mathieu J.M. Bertrand, Patrizia Agostinis, Geert Berx, Wim Declercq, Peter Vandenabeele, Dmitri V. Krysko
Published 2016-04-01