Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity.

by Stéphane Koundrioukoff, Sandra Carignon, Hervé Técher, Anne Letessier, Olivier Brison, Michelle Debatisse
Published 2013-01-01

The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin

by Serge Bauwens, Liudmyla Lototska, Stephane Koundrioukoff, Michelle Debatisse, Jing Ye, Eric Gilson, Aaron Mendez-Bermudez
Published 2021-03-01

Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage

by Hervé Técher, Stéphane Koundrioukoff, Sandra Carignon, Therese Wilhelm, Gaël A. Millot, Bernard S. Lopez, Olivier Brison, Michelle Debatisse
Published 2016-02-01

The RBBP6/ZBTB38/MCM10 Axis Regulates DNA Replication and Common Fragile Site Stability

by Benoit Miotto, Moredreck Chibi, Ping Xie, Stéphane Koundrioukoff, Hanlie Moolman-Smook, David Pugh, Michelle Debatisse, Fuchu He, Lingqiang Zhang, Pierre-Antoine Defossez
Published 2014-04-01

Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide

by Olivier Brison, Sami El-Hilali, Dana Azar, Stéphane Koundrioukoff, Mélanie Schmidt, Viola Nähse, Yan Jaszczyszyn, Anne-Marie Lachages, Bernard Dutrillaux, Claude Thermes, Michelle Debatisse, Chun-Long Chen
Published 2019-12-01