Fc receptors for immunoglobulins and their appearance during vertebrate evolution.

by Srinivas Akula, Sayran Mohammadamin, Lars Hellman
Published 2014-01-01

Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

by Zhirong Fu, Srinivas Akula, Michael Thorpe, Lars Hellman
Published 2020-01-01

Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

by Srinivas Akula, Michael Thorpe, Vamsi Boinapally, Lars Hellman
Published 2015-01-01

Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme

by Zhirong Fu, Srinivas Akula, Michael Thorpe, Lars Hellman
Published 2020-01-01

Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

by Zhirong Fu, Srinivas Akula, Michael Thorpe, Lars Hellman
Published 2019-10-01

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution.

by Zhirong Fu, Michael Thorpe, Srinivas Akula, Lars Hellman
Published 2016-01-01

Correction: Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

by Srinivas Akula, Michael Thorpe, Vamsi Boinapally, Lars Hellman
Published 2015-01-01

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

by Lars Torkel Hellman, Srinivas Akula, Michael Thorpe, Zhirong Fu
Published 2017-12-01

Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

by Petter Berglund, Srinivas Akula, Zhirong Fu, Michael Thorpe, Lars Hellman
Published 2020-11-01

Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extend...

by Zhirong Fu, Michael Thorpe, Srinivas Akula, Gurdeep Chahal, Lars T. Hellman
Published 2018-10-01

How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells

by Srinivas Akula, Aida Paivandy, Zhirong Fu, Michael Thorpe, Gunnar Pejler, Lars Hellman
Published 2020-09-01

Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity

by Srinivas Akula, Aida Paivandy, Zhirong Fu, Michael Thorpe, Gunnar Pejler, Lars Hellman
Published 2020-01-01

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

by Michael Thorpe, Zhirong Fu, Emanuelle Albat, Srinivas Akula, Lawrence de Garavilla, Jukka Kervinen, Lars Hellman
Published 2018-01-01

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

by Michael Thorpe, Zhirong Fu, Gurdeep Chahal, Srinivas Akula, Jukka Kervinen, Lawrence de Garavilla, Lars Hellman
Published 2018-01-01

Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity.

by Zhirong Fu, Srinivas Akula, Chang Qiao, Jinhye Ryu, Gurdeep Chahal, Lawrence de Garavilla, Jukka Kervinen, Michael Thorpe, Lars Hellman
Published 2021-01-01

Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33

by Andrea R. Teufelberger, Sharon Van Nevel, Paco Hulpiau, Paco Hulpiau, Maria Nordengrün, Savvas N. Savvides, Savvas N. Savvides, Sarah De Graeve, Srinivas Akula, Gabriele Holtappels, Natalie De Ruyck, Wim Declercq, Wim Declercq, Peter Vandenabeele, Peter Vandenabeele, Lars Hellman, Barbara M. Bröker, Dmitri V. Krysko, Dmitri V. Krysko, Dmitri V. Krysko, Claus Bachert, Claus Bachert, Claus Bachert, Olga Krysko, Olga Krysko
Published 2020-09-01