Data-Independent Acquisition Proteomics Reveals Long-Term Biomarkers in the Serum of C57BL/6J Mice Following Local High-Dose Heart Irradiation

by Omid Azimzadeh, Omid Azimzadeh, Christine von Toerne, Vikram Subramanian, Wolfgang Sievert, Gabriele Multhoff, Michael J. Atkinson, Michael J. Atkinson, Soile Tapio, Soile Tapio
Published 2021-07-01

Adhesion molecule expression and function of primary endothelial cells in benign and malignant tissues correlates with proliferation.

by Wolfgang Sievert, Soile Tapio, Stephanie Breuninger, Udo Gaipl, Nicolaus Andratschke, Klaus-Rüdiger Trott, Gabriele Multhoff
Published 2014-01-01

Integrative multiomics study for validation of mechanisms in radiation-induced ischemic heart disease in Mayak workers.

by Anna Papiez, Omid Azimzadeh, Tamara Azizova, Maria Moseeva, Natasa Anastasov, Jan Smida, Soile Tapio, Joanna Polanska
Published 2018-01-01

Radiation Response of Human Cardiac Endothelial Cells Reveals a Central Role of the cGAS-STING Pathway in the Development of Inflammation

by Jos Philipp, Ronan Le Gleut, Christine von Toerne, Prabal Subedi, Omid Azimzadeh, Michael J. Atkinson, Soile Tapio
Published 2020-10-01

Cell survival following radiation exposure requires miR-525-3p mediated suppression of ARRB1 and TXN1.

by Anne Kraemer, Zarko Barjaktarovic, Hakan Sarioglu, Klaudia Winkler, Friederike Eckardt-Schupp, Soile Tapio, Michael J Atkinson, Simone Moertl
Published 2013-01-01

Ionizing radiation-induced circulatory and metabolic diseases

by Soile Tapio, Mark P. Little, Jan Christian Kaiser, Nathalie Impens, Nobuyuki Hamada, Alexandros G. Georgakilas, David Simar, Sisko Salomaa
Published 2021-01-01

Long non-coding RNA PARTICLE bridges histone and DNA methylation

by Valerie Bríd O’Leary, Sarah Hain, Doris Maugg, Jan Smida, Omid Azimzadeh, Soile Tapio, Saak Victor Ovsepian, Michael John Atkinson
Published 2017-05-01

In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome.

by Mayur V Bakshi, Omid Azimzadeh, Juliane Merl-Pham, Tine Verreet, Stefanie M Hauck, Mohammed A Benotmane, Michael J Atkinson, Soile Tapio
Published 2016-01-01

Ionising radiation immediately impairs synaptic plasticity-associated cytoskeletal signalling pathways in HT22 cells and in mouse brain: an in vitro/in vivo comparison study.

by Stefan J Kempf, Sonja Buratovic, Christine von Toerne, Simone Moertl, Bo Stenerlöw, Stefanie M Hauck, Michael J Atkinson, Per Eriksson, Soile Tapio
Published 2014-01-01

Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE ^-/- Mi...

by Zarko Barjaktarovic, Juliane Merl-Pham, Ignacia Braga-Tanaka, Satoshi Tanaka, Stefanie M. Hauck, Anna Saran, Mariateresa Mancuso, Michael J. Atkinson, Soile Tapio, Omid Azimzadeh
Published 2019-10-01

The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation.

by Ramesh Yentrapalli, Omid Azimzadeh, Arundhathi Sriharshan, Katharina Malinowsky, Juliane Merl, Andrzej Wojcik, Mats Harms-Ringdahl, Michael J Atkinson, Karl-Friedrich Becker, Siamak Haghdoost, Soile Tapio
Published 2013-01-01

Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays.

by Zarko Barjaktarovic, Dominik Schmaltz, Alena Shyla, Omid Azimzadeh, Sabine Schulz, Julia Haagen, Wolfgang Dörr, Hakan Sarioglu, Alexander Schäfer, Michael J Atkinson, Hans Zischka, Soile Tapio
Published 2011-01-01

Chronic Occupational Exposure to Ionizing Radiation Induces Alterations in the Structure and Metabolism of the Heart: A Proteomic Analysis of Human Formalin-Fixed Paraffin-Embedded...

by Omid Azimzadeh, Tamara Azizova, Juliane Merl-Pham, Andreas Blutke, Maria Moseeva, Olga Zubkova, Natasa Anastasov, Annette Feuchtinger, Stefanie M. Hauck, Michael J. Atkinson, Soile Tapio
Published 2020-09-01

Radiation Exposure of Peripheral Mononuclear Blood Cells Alters the Composition and Function of Secreted Extracellular Vesicles

by Simone Moertl, Dominik Buschmann, Omid Azimzadeh, Michael Schneider, Rosemarie Kell, Klaudia Winkler, Soile Tapio, Sabine Hornhardt, Juliane Merl-Pham, Michael W. Pfaffl, Michael J. Atkinson
Published 2020-03-01

Phenotypic and Functional Characteristics of Exosomes Derived from Irradiated Mouse Organs and Their Role in the Mechanisms Driving Non-Targeted Effects

by Seda Tuncay Cagatay, Ammar Mayah, Mariateresa Mancuso, Paola Giardullo, Simonetta Pazzaglia, Anna Saran, Amuthachelvi Daniel, Damien Traynor, Aidan D. Meade, Fiona Lyng, Soile Tapio, Munira Kadhim
Published 2020-11-01

PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome

by Valerie Bríd O’Leary, Jan Smida, Fabian Andreas Buske, Laura Garcia Carrascosa, Omid Azimzadeh, Doris Maugg, Sarah Hain, Soile Tapio, Wolfgang Heidenreich, James Kerr, Matt Trau, Saak Victor Ovsepian, Michael John Atkinson
Published 2017-08-01

Out-of-Field Hippocampus from Partial-Body Irradiated Mice Displays Changes in Multi-Omics Profile and Defects in Neurogenesis

by Simonetta Pazzaglia, Barbara Tanno, Francesca Antonelli, Paola Giardullo, Gabriele Babini, Prabal Subedi, Omid Azimzadeh, Zohaib N. Khan, Kateryna Oleksenko, Fabian Metzger, Christine von Toerne, Damien Traynor, Dinesh Medipally, Aidan D. Meade, Munira Kadhim, Fiona M. Lyng, Soile Tapio, Anna Saran, Mariateresa Mancuso
Published 2021-04-01

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses

by Bjorn Baselet, Bjorn Baselet, Omid Azimzadeh, Nadine Erbeldinger, Nadine Erbeldinger, Mayur V. Bakshi, Till Dettmering, Ann Janssen, Svetlana Ktitareva, Donna J. Lowe, Arlette Michaux, Roel Quintens, Kenneth Raj, Marco Durante, Marco Durante, Claudia Fournier, Mohammed A. Benotmane, Sarah Baatout, Sarah Baatout, Pierre Sonveaux, Soile Tapio, An Aerts
Published 2017-09-01