SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro.

by Martijn J van Hemert, Sjoerd H E van den Worm, Kèvin Knoops, A Mieke Mommaas, Alexander E Gorbalenya, Eric J Snijder
Published 2008-05-01

Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture.

by Aartjan J W te Velthuis, Sjoerd H E van den Worm, Amy C Sims, Ralph S Baric, Eric J Snijder, Martijn J van Hemert
Published 2010-01-01

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum.

by Kèvin Knoops, Marjolein Kikkert, Sjoerd H E van den Worm, Jessika C Zevenhoven-Dobbe, Yvonne van der Meer, Abraham J Koster, A Mieke Mommaas, Eric J Snijder
Published 2008-09-01

Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination.

by Sjoerd H E van den Worm, Klara Kristin Eriksson, Jessika C Zevenhoven, Friedemann Weber, Roland Züst, Thomas Kuri, Ronald Dijkman, Guohui Chang, Stuart G Siddell, Eric J Snijder, Volker Thiel, Andrew D Davidson
Published 2012-01-01