A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis

by Maddalena Parafati, R. Jason Kirby, Sepideh Khorasanizadeh, Fraydoon Rastinejad, Siobhan Malany
Published 2018-09-01

An ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegans.

by Chi K Leung, Ying Wang, Siobhan Malany, Andrew Deonarine, Kevin Nguyen, Stefan Vasile, Keith P Choe
Published 2013-01-01

Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation

by Maddalena Parafati, Sang Hyo Bae, R. Jason Kirby, Martina Fitzek, Preeti Iyer, Ola Engkvist, David M. Smith, Siobhan Malany
Published 2020-12-01