Molecular Testing in CML between Old and New Methods: Are We at a Turning Point?

by Simona Soverini, Simona Bernardi, Sara Galimberti
Published 2020-11-01

Treatment and monitoring of Philadelphia chromosome-positive leukemia patients: recent advances and remaining challenges

by Simona Soverini, Renato Bassan, Thomas Lion
Published 2019-04-01

Chronic Myeloid Leukemia Prognosis and Therapy: Criticisms and Perspectives

by Domenico Russo, José Valentín Garcia-Gutierrez, Simona Soverini, Michele Baccarani
Published 2020-06-01

Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy

by Simona Soverini, Manuela Mancini, Luana Bavaro, Michele Cavo, Giovanni Martinelli
Published 2018-02-01

Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort?

by Simona Soverini, Sara De Santis, Cecilia Monaldi, Samantha Bruno, Manuela Mancini
Published 2021-06-01

Aurora kinase inhibitors: which role in the treatment of chronic myelogenous leukemia patients resistant to imatinib?

by Giovanni Martinelli, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Daniela Cilloni, Michele Baccarani
Published 2009-02-01

The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities

by Samantha Bruno, Manuela Mancini, Sara De Santis, Cecilia Monaldi, Michele Cavo, Simona Soverini
Published 2021-06-01

SYSTEMIC MASTOCYTOSIS: MOLECULAR LANDSCAPE AND IMPLICATIONS FOR TREATMENT

by Cecilia Monaldi, Sara De Santis, Manuela Mancini, Samantha Bruno, Michele Cavo, Simona Soverini
Published 2021-06-01

Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy

by Margherita Martelli, Cecilia Monaldi, Sara De Santis, Samantha Bruno, Manuela Mancini, Michele Cavo, Simona Soverini
Published 2020-06-01

Ponatinib as a Valid Alternative Strategy in Patients with Blast Crisis-Chronic Myeloid Leukemia Not Eligible for Allogeneic Stem Cells Transplantation and/or Conventional Chemothe...

by Cristina Bucelli, Daniele Cattaneo, Valeria Ferla, Manuela Zappa, Caterina de Benedittis, Simona Soverini, Alessandra Iurlo
Published 2017-01-01

BCR-ABL1-associated reduction of beta catenin antagonist Chibby1 in chronic myeloid leukemia.

by Elisa Leo, Manuela Mancini, Michela Aluigi, Simona Luatti, Fausto Castagnetti, Nicoletta Testoni, Simona Soverini, Maria Alessandra Santucci, Giovanni Martinelli
Published 2013-01-01

Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology

by Vlad Moisoiu, Patric Teodorescu, Patric Teodorescu, Lorand Parajdi, Sergiu Pasca, Mihnea Zdrenghea, Delia Dima, Radu Precup, Ciprian Tomuleasa, Ciprian Tomuleasa, Simona Soverini
Published 2019-09-01

The clonal evolution of two distinct T315I-positive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: a case report

by Caterina De Benedittis, Cristina Papayannidis, Claudia Venturi, Maria Chiara Abbenante, Stefania Paolini, Sarah Parisi, Chiara Sartor, Michele Cavo, Giovanni Martinelli, Simona Soverini
Published 2017-08-01

14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia.

by Manuela Mancini, Elisa Leo, Ken-Ichi Takemaru, Virginia Campi, Fausto Castagnetti, Simona Soverini, Caterina De Benedittis, Gianantonio Rosti, Michele Cavo, Maria Alessandra Santucci, Giovanni Martinelli
Published 2015-01-01

Interferon-α Revisited: Individualized Treatment Management Eased the Selective Pressure of Tyrosine Kinase Inhibitors on BCR-ABL1 Mutations Resulting in a Molecular Response in Hi...

by Vaclava Polivkova, Peter Rohon, Hana Klamova, Olga Cerna, Martina Divoka, Nikola Curik, Jan Zach, Martin Novak, Iuri Marinov, Simona Soverini, Edgar Faber, Katerina Machova Polakova
Published 2016-01-01

Next‐generation sequencing for BCR‐ABL1 kinase domain mutations in adult patients with Philadelphia chromosome‐positive acute lymphoblastic leukemia: A position paper

by Simona Soverini, Francesco Albano, Renato Bassan, Francesco Fabbiano, Felicetto Ferrara, Robin Foà, Attilio Olivieri, Alessandro Rambaldi, Giuseppe Rossi, Simona Sica, Giorgina Specchia, Adriano Venditti, Giovanni Barosi, Fabrizio Pane
Published 2020-05-01

Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper

by Simona Soverini, Elisabetta Abruzzese, Monica Bocchia, Massimiliano Bonifacio, Sara Galimberti, Antonella Gozzini, Alessandra Iurlo, Luigiana Luciano, Patrizia Pregno, Gianantonio Rosti, Giuseppe Saglio, Fabio Stagno, Mario Tiribelli, Paolo Vigneri, Giovanni Barosi, Massimo Breccia
Published 2019-12-01

Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a

by Maria Chiara Fontana, Jacopo Nanni, Andrea Ghelli Luserna di Rorà, Elisabetta Petracci, Antonella Padella, Martina Ghetti, Anna Ferrari, Giovanni Marconi, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Antonio Curti, Ernesta Audisio, Maria Benedetta Giannini, Michela Rondoni, Francesco Lanza, Michele Cavo, Giovanni Martinelli, Giorgia Simonetti
Published 2021-04-01

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.

by Ilaria Iacobucci, Nunzio Iraci, Monica Messina, Annalisa Lonetti, Sabina Chiaretti, Emanuele Valli, Anna Ferrari, Cristina Papayannidis, Francesca Paoloni, Antonella Vitale, Clelia Tiziana Storlazzi, Emanuela Ottaviani, Viviana Guadagnuolo, Sandra Durante, Marco Vignetti, Simona Soverini, Fabrizio Pane, Robin Foà, Michele Baccarani, Markus Müschen, Giovanni Perini, Giovanni Martinelli
Published 2012-01-01

Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia

by Samantha Bruno, Lorenza Bandini, Agnese Patuelli, Valentina Robustelli, Valentina Robustelli, Claudia Venturi, Manuela Mancini, Dorian Forte, Sara De Santis, Cecilia Monaldi, Alessandra Grassi, Gabriella Chiurumbolo, Stefania Paolini, Gianluca Cristiano, Cristina Papayannidis, Chiara Sartor, Jacopo Nanni, Emanuela Ottaviani, Antonio Curti, Michele Cavo, Michele Cavo, Simona Soverini
Published 2021-09-01