ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma

by Ewa Aladowicz, Letizia Granieri, Federica Marocchi, Simona Punzi, Giuseppina Giardina, Pier Francesco Ferrucci, Giovanni Mazzarol, Maria Capra, Giuseppe Viale, Stefano Confalonieri, Sara Gandini, Fiorenza Lotti, Luisa Lanfrancone
Published 2020-11-01

Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs

by Simona Punzi, Marine Meliksetian, Laura Riva, Federica Marocchi, Giancarlo Pruneri, Carmen Criscitiello, Franco Orsi, Lorenzo Spaggiari, Monica Casiraghi, Paolo Della Vigna, Lucilla Luzi, Giuseppe Curigliano, Pier Giuseppe Pelicci, Luisa Lanfrancone
Published 2019-06-01

WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells

by Simona Punzi, Chiara Balestrieri, Carolina D’Alesio, Daniela Bossi, Gaetano Ivan Dellino, Elena Gatti, Giancarlo Pruneri, Carmen Criscitiello, Giulia Lovati, Marine Meliksetyan, Alessandro Carugo, Giuseppe Curigliano, Gioacchino Natoli, Pier Giuseppe Pelicci, Luisa Lanfrancone
Published 2019-11-01

Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways

by Federica Invrea, Simona Punzi, Consalvo Petti, Rosalba Minelli, Michael D. Peoples, Christopher A. Bristow, Valentina Vurchio, Alessia Corrado, Alberto Bragoni, Caterina Marchiò, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Claudio Isella, Alessandro Carugo, Giulio F. Draetta, Enzo Medico
Published 2021-07-01