Simon Wain-Hobson

Simon Wain-Hobson (born 25 May 1953) is a British/French microbiologist, professor of molecular retrovirology at the Pasteur Institute in Paris, director of the French National HPV Reference Laboratory, and board chairman of the Foundation for Vaccine Research in Washington, D.C. Provided by Wikipedia
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  1. 1
    Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase.
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  2. 2
    Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.
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  3. 3
    Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.
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  4. 4
    Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death.
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  5. 5
    Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1.
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  6. 6
    Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
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  7. 7
    Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.
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  8. 8
    Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus
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