Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor.

by Simon Heidegger, Alexander Jarosch, Martina Schmickl, Stefan Endres, Carole Bourquin, Christian Hotz
Published 2015-01-01

Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines

by Sarah Bek, Florian Stritzke, Alexander Wintges, Tatiana Nedelko, Daniel F.R. Böhmer, Julius C. Fischer, Tobias Haas, Hendrik Poeck, Simon Heidegger
Published 2019-04-01

RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockadeResearch in context

by Simon Heidegger, Diana Kreppel, Michael Bscheider, Florian Stritzke, Tatiana Nedelko, Alexander Wintges, Sarah Bek, Julius C. Fischer, Theresa Graalmann, Ulrich Kalinke, Florian Bassermann, Tobias Haas, Hendrik Poeck
Published 2019-03-01