Reply to ‘Hypothermic machine perfusion before viability testing of previously discarded human livers’

by Hynek Mergental, Richard W. Laing, Simon C. Afford, Darius F. Mirza
Published 2021-02-01

Biomarkers of Liver Injury during Transplantation in an Era of Machine Perfusion

by Ricky H. Bhogal, Darius F. Mirza, Simon C. Afford, Hynek Mergental
Published 2020-02-01

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.

by Elizabeth H Humphreys, Kevin T Williams, David H Adams, Simon C Afford
Published 2010-11-01

Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation.

by Ricky H Bhogal, Christopher J Weston, Stuart M Curbishley, David H Adams, Simon C Afford
Published 2012-01-01

C4b binding protein binds to CD154 preventing CD40 mediated cholangiocyte apoptosis: a novel link between complement and epithelial cell survival.

by Kevin T Williams, Steven P Young, Alison Negus, Lawrence S Young, David H Adams, Simon C Afford
Published 2007-01-01

How Machine Perfusion Ameliorates Hepatic Ischaemia Reperfusion Injury

by George Clarke, Hynek Mergental, Angus Hann, M. Thamara P. R. Perera, Simon C. Afford, Darius F. Mirza
Published 2021-07-01

The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion

by Richard W. Laing, Richard W. Laing, Samantha Stubblefield, Lorraine Wallace, Valerie D. Roobrouck, Ricky H. Bhogal, Ricky H. Bhogal, Andrea Schlegel, Yuri L. Boteon, Yuri L. Boteon, Gary M. Reynolds, Anthony E. Ting, Darius F. Mirza, Darius F. Mirza, Philip N. Newsome, Philip N. Newsome, Hynek Mergental, Hynek Mergental, Simon C. Afford, Simon C. Afford
Published 2020-06-01

Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience.

by Ricky H Bhogal, James Hodson, David C Bartlett, Christopher J Weston, Stuart M Curbishley, Emma Haughton, Kevin T Williams, Gary M Reynolds, Phillip N Newsome, David H Adams, Simon C Afford
Published 2011-03-01

Ex situ Normothermic Split Liver Machine Perfusion: Protocol for Robust Comparative Controls in Liver Function Assessment Suitable for Evaluation of Novel Therapeutic Interventions...

by Joseph A. Attard, Joseph A. Attard, Joseph A. Attard, Daniel-Clement Osei-Bordom, Daniel-Clement Osei-Bordom, Yuri Boteon, Yuri Boteon, Yuri Boteon, Lorraine Wallace, Lorraine Wallace, Vincenzo Ronca, Vincenzo Ronca, Gary Reynolds, Gary Reynolds, M. T. P. R. Perera, Ye Htun Oo, Ye Htun Oo, Ye Htun Oo, Ye Htun Oo, Hynek Mergental, Hynek Mergental, Hynek Mergental, Darius F. Mirza, Simon C. Afford, Simon C. Afford
Published 2021-02-01

Correction: The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular h...

by Yuri L Boteon, Richard W Laing, Andrea Schlegel, Lorraine Wallace, Amanda Smith, Joseph Attard, Ricky H Bhogal, Gary Reynolds, M Thamara Pr Perera, Paolo Muiesan, Darius F Mirza, Hynek Mergental, Simon C Afford
Published 2020-01-01

The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-b...

by Yuri L Boteon, Richard W Laing, Andrea Schlegel, Lorraine Wallace, Amanda Smith, Joseph Attard, Ricky H Bhogal, Gary Reynolds, M Thamara PR Perera, Paolo Muiesan, Darius F Mirza, Hynek Mergental, Simon C Afford
Published 2019-01-01

Transplantation of discarded livers following viability testing with normothermic machine perfusion

by Hynek Mergental, Richard W. Laing, Amanda J. Kirkham, M. Thamara P. R. Perera, Yuri L. Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A. H. Neil, Stefan G. Hübscher, Paolo Muiesan, John R. Isaac, Keith J. Roberts, Manuel Abradelo, Andrea Schlegel, James Ferguson, Hentie Cilliers, Julian Bion, David H. Adams, Chris Morris, Peter J. Friend, Christina Yap, Simon C. Afford, Darius F. Mirza
Published 2020-06-01