Protective role of mirtazapine in adult female Mecp2 +/− mice and patients with Rett syndrome

by Javier Flores Gutiérrez, Claudio De Felice, Giulia Natali, Silvia Leoncini, Cinzia Signorini, Joussef Hayek, Enrico Tongiorgi
Published 2020-09-01

Isoprostanes and 4-Hydroxy-2-nonenal: Markers or Mediators of Disease? Focus on Rett Syndrome as a Model of Autism Spectrum Disorder

by Cinzia Signorini, Claudio De Felice, Thierry Durand, Camille Oger, Jean-Marie Galano, Silvia Leoncini, Alessandra Pecorelli, Giuseppe Valacchi, Lucia Ciccoli, Joussef Hayek
Published 2013-01-01

Genes Related to Mitochondrial Functions, Protein Degradation, and Chromatin Folding Are Differentially Expressed in Lymphomonocytes of Rett Syndrome Patients

by Alessandra Pecorelli, Guido Leoni, Franco Cervellati, Raffaella Canali, Cinzia Signorini, Silvia Leoncini, Alessio Cortelazzo, Claudio De Felice, Lucia Ciccoli, Joussef Hayek, Giuseppe Valacchi
Published 2013-01-01

Intestinal Candida parapsilosis isolates from Rett syndrome subjects bear potential virulent traits and capacity to persist within the host

by Francesco Strati, Antonio Calabrò, Claudio Donati, Claudio De Felice, Joussef Hayek, Olivier Jousson, Silvia Leoncini, Daniela Renzi, Lisa Rizzetto, Carlotta De Filippo, Duccio Cavalieri
Published 2018-05-01

Isoprostanoids in Clinical and Experimental Neurological Disease Models

by Cinzia Signorini, Claudio De Felice, Jean-Marie Galano, Camille Oger, Silvia Leoncini, Alessio Cortelazzo, Lucia Ciccoli, Thierry Durand, Joussef Hayek, Jetty Chung-Yung Lee
Published 2018-07-01

Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome: Relationships with Aberrant Redox Homeostasis, Inflammation, and ω-3 PUFAs

by Silvia Leoncini, Claudio De Felice, Cinzia Signorini, Gloria Zollo, Alessio Cortelazzo, Thierry Durand, Jean-Marie Galano, Roberto Guerranti, Marcello Rossi, Lucia Ciccoli, Joussef Hayek
Published 2015-01-01

Subclinical Inflammatory Status in Rett Syndrome

by Alessio Cortelazzo, Claudio De Felice, Roberto Guerranti, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Gloria Zollo, Claudia Landi, Giuseppe Valacchi, Lucia Ciccoli, Luca Bini, Joussef Hayek
Published 2014-01-01

Effects of ω-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome

by Silvia Maffei, Claudio De Felice, Pierpaolo Cannarile, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Barbara Montomoli, Stefano Lunghetti, Lucia Ciccoli, Thierry Durand, Roberto Favilli, Joussef Hayek
Published 2014-01-01

A Plasma Proteomic Approach in Rett Syndrome: Classical versus Preserved Speech Variant

by Alessio Cortelazzo, Roberto Guerranti, Claudio De Felice, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Claudia Landi, Luca Bini, Barbara Montomoli, Claudia Sticozzi, Lucia Ciccoli, Giuseppe Valacchi, Joussef Hayek
Published 2013-01-01

Circulating 4-F_4t-Neuroprostane and 10-F_4t-Neuroprostane Are Related to <i>MECP2</i> Gene Mutation and Natural History in Rett Syndrome

by Cinzia Signorini, Silvia Leoncini, Thierry Durand, Jean-Marie Galano, Alexandre Guy, Valérie Bultel-Poncé, Camille Oger, Jetty Chung-Yung Lee, Lucia Ciccoli, Joussef Hayek, Claudio De Felice
Published 2021-04-01

MECP2 Duplication Syndrome: Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome.

by Cinzia Signorini, Claudio De Felice, Silvia Leoncini, Rikke S Møller, Gloria Zollo, Sabrina Buoni, Alessio Cortelazzo, Roberto Guerranti, Thierry Durand, Lucia Ciccoli, Maurizio D'Esposito, Kirstine Ravn, Joussef Hayek
Published 2016-01-01

Persistent Unresolved Inflammation in the Mecp2-308 Female Mutated Mouse Model of Rett Syndrome

by Alessio Cortelazzo, Claudio De Felice, Bianca De Filippis, Laura Ricceri, Giovanni Laviola, Silvia Leoncini, Cinzia Signorini, Monica Pescaglini, Roberto Guerranti, Anna Maria Timperio, Lello Zolla, Lucia Ciccoli, Joussef Hayek
Published 2017-01-01

Beta-actin deficiency with oxidative posttranslational modifications in Rett syndrome erythrocytes: insights into an altered cytoskeletal organization.

by Alessio Cortelazzo, Claudio De Felice, Alessandra Pecorelli, Giuseppe Belmonte, Cinzia Signorini, Silvia Leoncini, Gloria Zollo, Antonietta Capone, Cinzia Della Giovampaola, Claudia Sticozzi, Giuseppe Valacchi, Lucia Ciccoli, Roberto Guerranti, Joussef Hayek
Published 2014-01-01

Erythrocyte Shape Abnormalities, Membrane Oxidative Damage, and β-Actin Alterations: An Unrecognized Triad in Classical Autism

by Lucia Ciccoli, Claudio De Felice, Eugenio Paccagnini, Silvia Leoncini, Alessandra Pecorelli, Cinzia Signorini, Giuseppe Belmonte, Roberto Guerranti, Alessio Cortelazzo, Mariangela Gentile, Gloria Zollo, Thierry Durand, Giuseppe Valacchi, Marcello Rossi, Joussef Hayek
Published 2013-01-01

F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome

by Claudio De Felice, Cinzia Signorini, Thierry Durand, Camille Oger, Alexandre Guy, Valérie Bultel-Poncé, Jean-Marie Galano, Lucia Ciccoli, Silvia Leoncini, Maurizio D'Esposito, Stefania Filosa, Alessandra Pecorelli, Giuseppe Valacchi, Joussef Hayek
Published 2011-12-01

Inflammatory Lung Disease in Rett Syndrome

by Claudio De Felice, Marcello Rossi, Silvia Leoncini, Glauco Chisci, Cinzia Signorini, Giuseppina Lonetti, Laura Vannuccini, Donatella Spina, Alessandro Ginori, Ingrid Iacona, Alessio Cortelazzo, Alessandra Pecorelli, Giuseppe Valacchi, Lucia Ciccoli, Tommaso Pizzorusso, Joussef Hayek
Published 2014-01-01

Effects of ω-3 Polyunsaturated Fatty Acids on Plasma Proteome in Rett Syndrome

by Claudio De Felice, Alessio Cortelazzo, Cinzia Signorini, Roberto Guerranti, Silvia Leoncini, Alessandra Pecorelli, Thierry Durand, Jean-Marie Galano, Camille Oger, Gloria Zollo, Barbara Montomoli, Claudia Landi, Luca Bini, Giuseppe Valacchi, Lucia Ciccoli, Joussef Hayek
Published 2013-01-01

Immune Dysfunction in Rett Syndrome Patients Revealed by High Levels of Serum Anti-N(Glc) IgM Antibody Fraction

by Anna Maria Papini, Francesca Nuti, Feliciana Real-Fernandez, Giada Rossi, Caterina Tiberi, Giuseppina Sabatino, Shashank Pandey, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Roberto Guerranti, Solange Lavielle, Lucia Ciccoli, Paolo Rovero, Claudio De Felice, Joussef Hayek
Published 2014-01-01

Redox Imbalance and Morphological Changes in Skin Fibroblasts in Typical Rett Syndrome

by Cinzia Signorini, Silvia Leoncini, Claudio De Felice, Alessandra Pecorelli, Ilaria Meloni, Francesca Ariani, Francesca Mari, Sonia Amabile, Eugenio Paccagnini, Mariangela Gentile, Giuseppe Belmonte, Gloria Zollo, Giuseppe Valacchi, Thierry Durand, Jean-Marie Galano, Lucia Ciccoli, Alessandra Renieri, Joussef Hayek
Published 2014-01-01

Revealing the complexity of a monogenic disease: rett syndrome exome sequencing.

by Elisa Grillo, Caterina Lo Rizzo, Laura Bianciardi, Veronica Bizzarri, Margherita Baldassarri, Ottavia Spiga, Simone Furini, Claudio De Felice, Cinzia Signorini, Silvia Leoncini, Alessandra Pecorelli, Lucia Ciccoli, Maria Antonietta Mencarelli, Joussef Hayek, Ilaria Meloni, Francesca Ariani, Francesca Mari, Alessandra Renieri
Published 2013-01-01