A probabilistic framework for cellular lineage reconstruction using integrated single-cell 5-hydroxymethylcytosine and genomic DNA sequencing

by Chatarin Wangsanuwat, Alex Chialastri, Javier F. Aldeguer, Nicolas C. Rivron, Siddharth S. Dey
Published 2021-08-01

Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion

by Chatarin Wangsanuwat, Kellie A. Heom, Estella Liu, Michelle A. O’Malley, Siddharth S. Dey
Published 2020-10-01

An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure

by Joanna J. Gell, Wanlu Liu, Enrique Sosa, Alex Chialastri, Grace Hancock, Yu Tao, Sissy E. Wamaitha, Grace Bower, Siddharth S. Dey, Amander T. Clark
Published 2020-03-01

Control over single-cell distribution of G1 lengths by WNT governs pluripotency.

by Jiwon Jang, Dasol Han, Mahdi Golkaram, Morgane Audouard, Guojing Liu, Daniel Bridges, Stefan Hellander, Alex Chialastri, Siddharth S Dey, Linda R Petzold, Kenneth S Kosik
Published 2019-09-01

Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development

by Maya Sen, Dylan Mooijman, Alex Chialastri, Jean-Charles Boisset, Mina Popovic, Björn Heindryckx, Susana M. Chuva de Sousa Lopes, Siddharth S. Dey, Alexander van Oudenaarden
Published 2021-02-01