PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants

by Chie Emoto, Trevor N. Johnson, Sibylle Neuhoff, David Hahn, Alexander A. Vinks, Tsuyoshi Fukuda
Published 2018-07-01

Acamprosate is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug–Drug Interaction...

by Irina E. Antonescu, Maria Karlgren, Maria L. Pedersen, Ivailo Simoff, Christel A.S. Bergström, Sibylle Neuhoff, Per Artursson, Bente Steffansen, Carsten Uhd Nielsen
Published 2020-04-01