Targeting CAR to the Peptide-MHC Complex Reveals Distinct Signaling Compared to That of TCR in a Jurkat T Cell Model

by Ling Wu, Joanna Brzostek, Shvetha Sankaran, Qianru Wei, Jiawei Yap, Triscilla Y.Y. Tan, Junyun Lai, Paul A. MacAry, Nicholas R. J. Gascoigne
Published 2021-02-01

Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling

by Xiang Zhao, Shvetha Sankaran, Jiawei Yap, Chien Tei Too, Zi Zong Ho, Garry Dolton, Mateusz Legut, Ee Chee Ren, Andrew K. Sewell, Antonio Bertoletti, Paul A. MacAry, Joanna Brzostek, Nicholas R. J. Gascoigne
Published 2018-07-01