Identification of Dehydroxytrichostatin A as a Novel Up-Regulator of the ATP-Binding Cassette Transporter A1 (ABCA1)

by Shuyi Si, Bin Hong, Yi Bao, Yanni Xu, Yang Xu
Published 2011-08-01

Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method

by Yan Li, Hongmin Sun, Xiaohong Zhu, Cong Bian, Yanchang Wang, Shuyi Si
Published 2019-08-01

E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro

by Ni Li, Xiao Wang, Peng Liu, Duo Lu, Wei Jiang, Yanni Xu, Shuyi Si
Published 2016-05-01

Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells

by Yanni Xu, Peng Liu, Suowen Xu, Marina Koroleva, Shuya Zhang, Shuyi Si, Zheng Gen Jin
Published 2017-07-01

Identification of anti-Gram-negative bacteria agents targeting the interaction between ribosomal proteins L12 and L10

by Weiwei Wang, Chao Liu, Ningyu Zhu, Yuan Lin, Jiandong Jiang, Yanchang Wang, Yan Li, Shuyi Si
Published 2018-09-01

IMB2026791, a Xanthone, Stimulates Cholesterol Efflux by Increasing the Binding of Apolipoprotein A-I to ATP-Binding Cassette Transporter A1

by Zijian Xie, Bin Hong, Zhuorong Li, Wei Jiang, Tingting Feng, Yanni Xu, Zhongbing Zhang, Jikai Liu, Shuyi Si
Published 2012-03-01

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

by Jianhua Gong, Yanbo Zheng, Ying Wang, Weijin Sheng, Yi Li, Xiujun Liu, Shuyi Si, Rongguang Shao, Yongsu Zhen
Published 2018-01-01

IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathway

by Dong Liu, Xinran Qiao, Zhijuan Ge, Yue Shang, Yi Li, Wendie Wang, Minghua Chen, Shuyi Si, Shu-zhen Chen
Published 2019-03-01

Comparative genomics and transcriptomics analyses provide insights into the high yield and regulatory mechanism of Norvancomycin biosynthesis in Amycolatopsis orientalis NCPC 2-48

by Xingxing Li, Cong Zhang, Ying Zhao, Xuan Lei, Zhibo Jiang, Xuexia Zhang, Zhihui Zheng, Shuyi Si, Lifei Wang, Bin Hong
Published 2021-02-01

Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA–BamD Interaction

by Yan Li, Xiaohong Zhu, Jing Zhang, Yuan Lin, Yuan Lin, Xuefu You, Minghua Chen, Yanchang Wang, Ningyu Zhu, Shuyi Si
Published 2020-06-01

A series of beta-carboline derivatives inhibit the kinase activity of PLKs.

by Xiaomin Han, Jing Zhang, Liang Guo, Rihui Cao, Yongzhen Li, Ni Li, Qin Ma, Jialin Wu, Yanchang Wang, Shuyi Si
Published 2012-01-01

A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α

by Xuelei Wang, Xiaofang Chen, Xiumin Zhang, Chunyan Su, Mengxia Yang, Wei He, Yu Du, Shuyi Si, Li Wang, Bin Hong
Published 2020-02-01

A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy-Related Bone Loss in Rats

by Xiaowan Han, Shiqiang Gong, Shiqiang Gong, Ni Li, Xiao Wang, Peng Liu, Yanni Xu, Xiaobo He, Wei Jiang, Shuyi Si
Published 2019-03-01

4862F, a New Inhibitor of HIV-1 Protease, from the Culture of Streptomyces I03A-04862

by Peizhen Tao, Wei Jiang, Liyan Yu, Minghua Chen, Shuoke Bai, Yexiang Wu, Xiuyong Fan, Yuqin Zhang, Yongzhen Li, Tian Zhang, Biao Dong, Maoluo Gan, Xiao Liu, Shuyi Si
Published 2012-12-01

Nuclear Factor Erythroid 2 Related Factor 2 Activator JC-5411 Inhibits Atherosclerosis Through Suppression of Inflammation and Regulation of Lipid Metabolism

by Xinhai Jiang, Yining Li, Weizhi Wang, Xiaowan Han, Jiangxue Han, Mingzhu Chen, Jing Zhang, Chenyin Wang, Shunwang Li, Jinque Luo, Xiao Wang, Yang Xu, Yanni Xu, Jingcai Cheng, Shuyi Si
Published 2020-11-01

Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT[S]

by Yanni Xu, Qi Liu, Yang Xu, Chang Liu, Xiao Wang, Xiaobo He, Ningyu Zhu, Jikai Liu, Yexiang Wu, Yongzhen Li, Ni Li, Tingting Feng, Fangfang Lai, Murui Zhang, Bin Hong, Jian-Dong Jiang, Shuyi Si
Published 2014-08-01