Screening-Based Chemical Approaches to Unravel Stem Cell Biology

by Shuibing Chen
Published 2018-12-01

Human pluripotent stem cell-based organoids and cell platforms for modelling SARS-CoV-2 infection and drug discovery

by Alice Maria Giani, Shuibing Chen
Published 2021-05-01

Modeling cancer progression using human pluripotent stem cell-derived cells and organoids

by Meili Zhang, J. Jeya Vandana, Lauretta Lacko, Shuibing Chen
Published 2020-12-01

Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling

by Su-Yi Tsai, Karen Maass, Jia Lu, Glenn I. Fishman, Shuibing Chen, Todd Evans
Published 2015-06-01

Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation

by Lingling Feng, Brandoch Cook, Su-Yi Tsai, Ting Zhou, Brooke LaFlamme, Todd Evans, Shuibing Chen
Published 2016-05-01

Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E

by Min Guo, Tuo Zhang, Xue Dong, Jenny Zhaoying Xiang, Minxiang Lei, Todd Evans, Johannes Graumann, Shuibing Chen
Published 2017-05-01

Derivation and characterization of a UCP1 reporter human ES cell line

by Suranjit Mukherjee, Tuo Zhang, Lauretta A. Lacko, Lei Tan, Jenny Zhaoying Xiang, Jason M. Butler, Shuibing Chen
Published 2018-07-01

Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling

by Der-I Kao, Lauretta A. Lacko, Bi-Sen Ding, Chen Huang, Kathleen Phung, Guoqiang Gu, Shahin Rafii, Heidi Stuhlmann, Shuibing Chen
Published 2015-02-01

ROCKII inhibition promotes the maturation of human pancreatic beta-like cells

by Zaniar Ghazizadeh, Der-I Kao, Sadaf Amin, Brandoch Cook, Sahana Rao, Ting Zhou, Tuo Zhang, Zhaoying Xiang, Reyn Kenyon, Omer Kaymakcalan, Chengyang Liu, Todd Evans, Shuibing Chen
Published 2017-08-01

Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry

by Rodrigo R. R. Duarte, Dennis C. Copertino, Luis P. Iñiguez, Jez L. Marston, Yaron Bram, Yuling Han, Robert E. Schwartz, Shuibing Chen, Douglas F. Nixon, Timothy R. Powell
Published 2021-09-01

Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells

by Lei Tan, Lauretta A. Lacko, Ting Zhou, Delia Tomoiaga, Romulo Hurtado, Tuo Zhang, Ana Sevilla, Aaron Zhong, Christopher E Mason, Scott Noggle, Todd Evans, Heidi Stuhlmann, Robert E. Schwartz, Shuibing Chen
Published 2019-09-01

PRMT5-mediated regulation of developmental myelination

by Antonella Scaglione, Julia Patzig, Jialiang Liang, Rebecca Frawley, Jabez Bok, Angeliki Mela, Camila Yattah, Jingxian Zhang, Shun Xie Teo, Ting Zhou, Shuibing Chen, Emily Bernstein, Peter Canoll, Ernesto Guccione, Patrizia Casaccia
Published 2018-07-01

Discovery of a drug candidate for GLIS3-associated diabetes

by Sadaf Amin, Brandoch Cook, Ting Zhou, Zaniar Ghazizadeh, Raphael Lis, Tuo Zhang, Mona Khalaj, Miguel Crespo, Manuradhi Perera, Jenny Zhaoying Xiang, Zengrong Zhu, Mark Tomishima, Chengyang Liu, Ali Naji, Todd Evans, Danwei Huangfu, Shuibing Chen
Published 2018-07-01

An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

by Logan A. Walsh, Mariano J. Alvarez, Erich Y. Sabio, Marsha Reyngold, Vladimir Makarov, Suranjit Mukherjee, Ken-Wing Lee, Alexis Desrichard, Şevin Turcan, Martin G. Dalin, Vinagolu K. Rajasekhar, Shuibing Chen, Linda T. Vahdat, Andrea Califano, Timothy A. Chan
Published 2017-08-01

A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival

by Ting Zhou, Tae Wan Kim, Chi Nok Chong, Lei Tan, Sadaf Amin, Zohreh Sadat Badieyan, Suranjit Mukherjee, Zaniar Ghazizadeh, Hui Zeng, Min Guo, Miguel Crespo, Tuo Zhang, Reyn Kenyon, Christopher L. Robinson, Effie Apostolou, Hui Wang, Jenny Zhaoying Xiang, Todd Evans, Lorenz Studer, Shuibing Chen
Published 2018-11-01

Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes

by Yvonne Sleiman, Monia Souidi, Ritu Kumar, Ellen Yang, Fabrice Jaffré, Ting Zhou, Albin Bernardin, Steve Reiken, Olivier Cazorla, Andrey V. Kajava, Adrien Moreau, Jean-Luc Pasquié, Andrew R. Marks, Bruce B. Lerman, Shuibing Chen, Jim W. Cheung, Todd Evans, Alain Lacampagne, Albano C. Meli
Published 2020-10-01

Male germ cells support long-term propagation of Zika virus

by Christopher L. Robinson, Angie C. N. Chong, Alison W. Ashbrook, Ginnie Jeng, Julia Jin, Haiqi Chen, Elizabeth I. Tang, Laura A. Martin, Rosa S. Kim, Reyn M. Kenyon, Eileen Do, Joseph M. Luna, Mohsan Saeed, Lori Zeltser, Harold Ralph, Vanessa L. Dudley, Marc Goldstein, Charles M. Rice, C. Yan Cheng, Marco Seandel, Shuibing Chen
Published 2018-05-01