Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery: Hypoxia-Inducible Factor-1 (HIF-1)-Active Cells as a Target for Cancer Therapy

by Shinae Kizaka-Kondoh, Takahiro Kuchimaru, Tetsuya Kadonosono
Published 2011-01-01

Optical Imaging of Tumor Hypoxia and Evaluation of Efficacy of a Hypoxia-Targeting Drug in Living Animals

by Hiroshi Harada, Shinae Kizaka-Kondoh, Masahiro Hiraoka
Published 2005-07-01

Slicing Spheroids in Microfluidic Devices for Morphological and Immunohistochemical Analysis

by Satoru Kuriu, Tetsuya Kadonosono, Shinae Kizaka-Kondoh, Tadashi Ishida
Published 2020-05-01

Uniform Cell Distribution Achieved by Using Cell Deformation in a Micropillar Array

by Maho Kaminaga, Tadashi Ishida, Tetsuya Kadonosono, Shinae Kizaka-Kondoh, Toru Omata
Published 2015-04-01

Microfluidic Device for Screening for Target Cell-Specific Binding Molecules by Using Adherent Cells

by Maho Kaminaga, Tadashi Ishida, Tetsuya Kadonosono, Shinae Kizaka-Kondoh, Toru Omata
Published 2019-01-01

Microfluidic High-Migratory Cell Collector Suppressing Artifacts Caused by Microstructures

by Tadashi Ishida, Takuya Shimamoto, Maho Kaminaga, Takahiro Kuchimaru, Shinae Kizaka-Kondoh, Toru Omata
Published 2019-02-01

In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system.

by Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Takashi Ushiki, Masahiro Hiraoka, Shinae Kizaka-Kondoh
Published 2010-12-01

A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries

by Takahiro Kuchimaru, Naoya Kataoka, Kenji Nakagawa, Tatsuhiro Isozaki, Hitomi Miyabara, Misa Minegishi, Tetsuya Kadonosono, Shinae Kizaka-Kondoh
Published 2018-07-01

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

by Takahiro Kuchimaru, Satoshi Iwano, Masahiro Kiyama, Shun Mitsumata, Tetsuya Kadonosono, Haruki Niwa, Shojiro Maki, Shinae Kizaka-Kondoh
Published 2016-06-01

A fluorescent protein scaffold for presenting structurally constrained peptides provides an effective screening system to identify high affinity target-binding peptides.

by Tetsuya Kadonosono, Etsuri Yabe, Tadaomi Furuta, Akihiro Yamano, Takuya Tsubaki, Takuya Sekine, Takahiro Kuchimaru, Minoru Sakurai, Shinae Kizaka-Kondoh
Published 2014-01-01

In Vivo Visualization of Heterogeneous Intratumoral Distribution of Hypoxia-Inducible Factor-1α Activity by the Fusion of High-Resolution SPECT and Morphological Imaging Tests

by Hirofumi Fujii, Masayuki Yamaguchi, Kazumasa Inoue, Yasuko Mutou, Masashi Ueda, Hideo Saji, Shinae Kizaka-Kondoh, Noriyuki Moriyama, Izumi O. Umeda
Published 2012-01-01

VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells

by Ayumi Yoshida, Akio Shimizu, Hirotsugu Asano, Tetsuya Kadonosono, Shinae Kizaka Kondoh, Elena Geretti, Akiko Mammoto, Michael Klagsbrun, Misuzu Kurokawa Seo
Published 2015-09-01

In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe.

by Youshi Fujita, Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Yoshiki Hase, Hidekazu Tomimoto, Masahiro Hiraoka, Shinae Kizaka-Kondoh, Masafumi Ihara, Ryosuke Takahashi
Published 2012-01-01

Noninvasive tracking of donor cell homing by near-infrared fluorescence imaging shortly after bone marrow transplantation.

by Takashi Ushiki, Shinae Kizaka-Kondoh, Eishi Ashihara, Shotaro Tanaka, Masayoshi Masuko, Hideyo Hirai, Shinya Kimura, Yoshifusa Aizawa, Taira Maekawa, Masahiro Hiraoka
Published 2010-01-01

Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging.

by Tetsuya Kadonosono, Takahiro Kuchimaru, Shuichi Yamada, Yumi Takahashi, Atsushi Murakami, Taeko Tani, Hitomi Watanabe, Tomoharu Tanaka, Kiichi Hirota, Masahiro Inoue, Tetsuya Tsukamoto, Takeshi Toyoda, Koji Urano, Kazuhiko Machida, Tomoo Eto, Tomoyuki Ogura, Hideki Tsutsumi, Mamoru Ito, Masahiro Hiraoka, Gen Kondoh, Shinae Kizaka-Kondoh
Published 2011-01-01