Systems-Level Response to Point Mutations in a Core Metabolic Enzyme Modulates Genotype-Phenotype Relationship

by Shimon Bershtein, Jeong-Mo Choi, Sanchari Bhattacharyya, Bogdan Budnik, Eugene Shakhnovich
Published 2015-04-01

Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype

by Sanchari Bhattacharyya, Shimon Bershtein, Bharat V Adkar, Jaie Woodard, Eugene I Shakhnovich
Published 2021-06-01

Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity

by Sanchari Bhattacharyya, Shimon Bershtein, Jin Yan, Tijda Argun, Amy I Gilson, Sunia A Trauger, Eugene I Shakhnovich
Published 2016-12-01

Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning

by Geut Galai, Hila Ben-David, Liron Levin, Martin F. Orth, Thomas G. P. Grünewald, Shai Pilosof, Shimon Bershtein, Barak Rotblat
Published 2020-03-01

Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in Bacteria.

by Shimon Bershtein, Adrian W R Serohijos, Sanchari Bhattacharyya, Michael Manhart, Jeong-Mo Choi, Wanmeng Mu, Jingwen Zhou, Eugene I Shakhnovich
Published 2015-10-01