The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase.

by Shunsuke Mori, Shigeyuki Nada, Hironobu Kimura, Shoji Tajima, Yusuke Takahashi, Ayaka Kitamura, Chitose Oneyama, Masato Okada
Published 2014-01-01

β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

by Woei-Yaw Chee, Yuriko Kurahashi, Junhyeong Kim, Kyoko Miura, Daisuke Okuzaki, Tohru Ishitani, Kentaro Kajiwara, Shigeyuki Nada, Hideyuki Okano, Masato Okada
Published 2021-03-01

Structural basis for the assembly of the Ragulator-Rag GTPase complex

by Ryo Yonehara, Shigeyuki Nada, Tomokazu Nakai, Masahiro Nakai, Ayaka Kitamura, Akira Ogawa, Hirokazu Nakatsumi, Keiichi I. Nakayama, Songling Li, Daron M. Standley, Eiki Yamashita, Atsushi Nakagawa, Masato Okada
Published 2017-11-01

The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II

by Takeshi Nakatani, Kohei Tsujimoto, JeongHoon Park, Tatsunori Jo, Tetsuya Kimura, Yoshitomo Hayama, Hachiro Konaka, Takayoshi Morita, Yasuhiro Kato, Masayuki Nishide, Shyohei Koyama, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh
Published 2021-06-01

Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals

by Tetsuya Kimura, Shigeyuki Nada, Noriko Takegahara, Tatsusada Okuno, Satoshi Nojima, Sujin Kang, Daisuke Ito, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuichi Mitsui, Natsuki Sakurai, Hana Sarashina-Kida, Masayuki Nishide, Yohei Maeda, Hyota Takamatsu, Daisuke Okuzaki, Masaki Yamada, Masato Okada, Atsushi Kumanogoh
Published 2016-10-01

Erratum: Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals

by Tetsuya Kimura, Shigeyuki Nada, Noriko Takegahara, Tatsusada Okuno, Satoshi Nojima, Sujin Kang, Daisuke Ito, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuichi Mitsui, Natsuki Sakurai, Hana Sarashina-Kida, Masayuki Nishide, Yohei Maeda, Hyota Takamatsu, Daisuke Okuzaki, Masaki Yamada, Masato Okada, Atsushi Kumanogoh
Published 2017-02-01