Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections

by Rui Zhang, Xiaohua Jiang, Jingxin Qiao, Zeng Wang, Aiping Tong, Jinliang Yang, Shengyong Yang, Li Yang
Published 2021-04-01

Capsule Networks Showed Excellent Performance in the Classification of hERG Blockers/Nonblockers

by Yiwei Wang, Yiwei Wang, Lei Huang, Lei Huang, Siwen Jiang, Yifei Wang, Jun Zou, Hongguang Fu, Shengyong Yang
Published 2020-01-01

A highly potent and selective inhibitor Roxyl-WL targeting IDO1 promotes immune response against melanoma

by Guangwei Xu, Tianqi Wang, Yongtao Li, Zhi Huang, Xin Wang, Jianyu Zheng, Shengyong Yang, Yan Fan, Rong Xiang
Published 2018-01-01

Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer

by Wen Peng, Huaqing Zhang, Shisheng Tan, Yan Li, Yang Zhou, Liang Wang, Chunqi Liu, Qiu Li, Xiaobo Cen, Shengyong Yang, Yinglan Zhao
Published 2020-07-01

Small molecules in targeted cancer therapy: advances, challenges, and future perspectives

by Lei Zhong, Yueshan Li, Liang Xiong, Wenjing Wang, Ming Wu, Ting Yuan, Wei Yang, Chenyu Tian, Zhuang Miao, Tianqi Wang, Shengyong Yang
Published 2021-05-01

Novel CDKs inhibitors for the treatment of solid tumour by simultaneously regulating the cell cycle and transcription control

by Xin Wang, Kaiyuan Deng, Cheng Wang, Yao Li, Tianqi Wang, Zhi Huang, Yakun Ma, Peiqing Sun, Yi Shi, Shengyong Yang, Yan Fan, Rong Xiang
Published 2020-01-01

Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

by Wei Yan, Lin Cheng, Wei Wang, Chao Wu, Xin Yang, Xiaozhe Du, Liang Ma, Shiqian Qi, Yuquan Wei, Zhiliang Lu, Shengyong Yang, Zhenhua Shao
Published 2020-10-01

Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells

by Jun Luo, Yoshinobu Odaka, Zhu Huang, Bing Cheng, Wang Liu, Lin Li, Chaowei Shang, Chao Zhang, Yang Wu, Yan Luo, Shengyong Yang, Peter J. Houghton, Xiaofeng Guo, Shile Huang
Published 2021-06-01

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines

by Wei Yan, Tao Yang, Jianhong Yang, Taijin Wang, Yamei Yu, Yuxi Wang, Qiang Chen, Peng Bai, Dan Li, Haoyu Ye, Qiang Qiu, Yongzhao Zhou, Yiguo Hu, Shengyong Yang, Yuquan Wei, Weimin Li, Lijuan Chen
Published 2018-05-01

Structural and Functional Insights into an Archaeal Lipid Synthase

by Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng
Published 2020-10-01

Structural and Functional Insights into an Archaeal Lipid Synthase

by Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng
Published 2021-05-01