Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses.

by Farhat Khan, Mike Porter, Robert Schwenk, Margot DeBot, Philippe Saudan, Sheetij Dutta
Published 2015-01-01

Novel sporozoite-based ELISpot assay to assess frequency of parasite-specific B cells after vaccination with irradiated sporozoites

by Tanmaya Atre, Tanisha M. Robinson, Tatyana Savransky, Sheetij Dutta, Judith E. Epstein, Elke S. Bergmann-Leitner
Published 2019-05-01

Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination

by Jessica S. Bolton, Sidhartha Chaudhury, Sheetij Dutta, Scott Gregory, Emily Locke, Tony Pierson, Elke S. Bergmann-Leitner
Published 2020-04-01

Blood Interferon Signatures Putatively Link Lack of Protection Conferred by the RTS,S Recombinant Malaria Vaccine to an Antigen-specific IgE Response [version 2; referees: 2 approv...

by Darawan Rinchai, Scott Presnell, Marta Vidal, Sheetij Dutta, Virander Chauhan, David Cavanagh, Gemma Moncunill, Carlota Dobaño, Damien Chaussabel
Published 2017-07-01

Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis

by Sidhartha Chaudhury, Jason A. Regules, Christian A. Darko, Sheetij Dutta, Anders Wallqvist, Norman C. Waters, Erik Jongert, Franck Lemiale, Elke S. Bergmann-Leitner
Published 2017-08-01

Comparison of immunogenicity and safety outcomes of a malaria vaccine FMP013/ALFQ in rhesus macaques (Macaca mulatta) of Indian and Chinese origin

by Monica L. Martin, Alexis A. Bitzer, Andrew Schrader, Elke S. Bergmann-Leitner, Kim Soto, Xiaoyan Zou, Zoltan Beck, Gary R. Matyas, Sheetij Dutta
Published 2019-11-01

IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.

by Robert Schwenk, Margot DeBot, Michael Porter, Jennifer Nikki, Lisa Rein, Roberta Spaccapelo, Andrea Crisanti, Paul D Wightman, Christian F Ockenhouse, Sheetij Dutta
Published 2014-01-01

Seroprevalence of Antibodies against Plasmodium falciparum Sporozoite Antigens as Predictive Disease Transmission Markers in an Area of Ghana with Seasonal Malaria Transmission.

by Kwadwo A Kusi, Samuel Bosomprah, Eric Kyei-Baafour, Emmanuel K Dickson, Bernard Tornyigah, Evelina Angov, Sheetij Dutta, Daniel Dodoo, Martha Sedegah, Kwadwo A Koram
Published 2016-01-01

Associations between antibodies to a panel of Plasmodium falciparum specific antigens and response to sub-optimal antimalarial therapy in Kampala, Uganda.

by Chris E Keh, Aashish R Jha, Bridget Nzarubara, David E Lanar, Sheetij Dutta, Michael Theisen, Philip J Rosenthal, Grant Dorsey, Douglas F Nixon, Bryan Greenhouse
Published 2012-01-01

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens.

by Joseph J Campo, Carlota Dobaño, Jahit Sacarlal, Caterina Guinovart, Alfredo Mayor, Evelina Angov, Sheetij Dutta, Chetan Chitnis, Eusebio Macete, John J Aponte, Pedro L Alonso
Published 2011-01-01

Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL

by Geneviève M. Labbé, Kazutoyo Miura, Sarah E. Silk, Wenjuan Gu, James E. Moon, Jing Jin, Ruth O. Payne, Michael P. Fay, Sheetij Dutta, Carole A. Long, Simon J. Draper
Published 2019-09-01

High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model.

by Sheetij Dutta, JoAnn S Sullivan, Katharine K Grady, J David Haynes, Jack Komisar, Adrian H Batchelor, Lorraine Soisson, Carter L Diggs, D Gray Heppner, David E Lanar, William E Collins, John W Barnwell
Published 2009-12-01

Surveillance for malaria elimination in Swaziland: a national cross-sectional study using pooled PCR and serology.

by Michelle S Hsiang, Jimee Hwang, Simon Kunene, Chris Drakeley, Deepika Kandula, Joseph Novotny, Justin Parizo, Trevor Jensen, Marcus Tong, Jordan Kemere, Sabelo Dlamini, Bruno Moonen, Evelina Angov, Sheetij Dutta, Christian Ockenhouse, Grant Dorsey, Bryan Greenhouse
Published 2012-01-01

In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP)

by Merricka C. Livingstone, Alexis A. Bitzer, Alish Giri, Kun Luo, Rajeshwer S. Sankhala, Misook Choe, Xiaoyan Zou, S. Moses Dennison, Yuanzhang Li, William Washington, Viseth Ngauy, Georgia D. Tomaras, M. Gordon Joyce, Adrian H. Batchelor, Sheetij Dutta
Published 2021-03-01

Analysis of factors affecting the variability of a quantitative suspension bead array assay measuring IgG to multiple Plasmodium antigens.

by Itziar Ubillos, Ruth Aguilar, Hector Sanz, Alfons Jiménez, Marta Vidal, Aida Valmaseda, Yan Dong, Deepak Gaur, Chetan E Chitnis, Sheetij Dutta, Evelina Angov, John J Aponte, Joseph J Campo, Clarissa Valim, Jaroslaw Harezlak, Carlota Dobaño
Published 2018-01-01

Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-...

by Itziar Ubillos, Alfons Jiménez, Marta Vidal, Paul W. Bowyer, Deepak Gaur, Sheetij Dutta, Benoit Gamain, Ross Coppel, Virander Chauhan, David Lanar, Chetan Chitnis, Evelina Angov, James Beeson, David Cavanagh, Joseph J. Campo, Ruth Aguilar, Carlota Dobaño
Published 2018-06-01

Correction: Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1.

by Sheetij Dutta, Lisa S. Dlugosz, Damien R. Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I. Rovira, J. Kathleen Moch, Meng Shi, Carole A. Long, Michael Foley, James G. Beeson, Robin F. Anders, Kazutoyo Miura, J. David Haynes, Adrian H. Batchelor
Published 2014-01-01

Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.

by Sheetij Dutta, Lisa S Dlugosz, Damien R Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I Rovira, J Kathleen Moch, Meng Shi, Carole A Long, Michael Foley, James G Beeson, Robin F Anders, Kazutoyo Miura, J David Haynes, Adrian H Batchelor
Published 2013-01-01

Cytokine and antibody responses to Plasmodium falciparum in naïve individuals during a first malaria episode: effect of age and malaria exposure.

by Gemma Moncunill, Alfredo Mayor, Alfons Jiménez, Augusto Nhabomba, Laura Puyol, Maria N Manaca, Diana Barrios, Pau Cisteró, Caterina Guinovart, Ruth Aguilar, Azucena Bardají, María-Jesús Pinazo, Evelina Angov, Sheetij Dutta, Chetan E Chitnis, José Muñoz, Joaquim Gascón, Carlota Dobaño
Published 2013-01-01

Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya

by Grace E. Weber, Michael T. White, Anna Babakhanyan, Peter Odada Sumba, John Vulule, Dylan Ely, Chandy John, Evelina Angov, David Lanar, Sheetij Dutta, David L. Narum, Toshihiro Horii, Alan Cowman, James Beeson, Joseph Smith, James W. Kazura, Arlene E. Dent
Published 2017-12-01