TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner.

by Molly Ohainle, Kyusik Kim, Sevnur Komurlu Keceli, Abby Felton, Ed Campbell, Jeremy Luban, Michael Emerman
Published 2020-04-01

Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α.

by Sevnur Kömürlü, Margret Bradley, Nikolai Smolin, Sabrina Imam, Raymond F Pauszek, Seth L Robia, David Millar, Emi E Nakayama, Tatsuo Shioda, Edward M Campbell
Published 2019-01-01

TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.

by Marcin D Roganowicz, Sevnur Komurlu, Santanu Mukherjee, Jacek Plewka, Steven L Alam, Katarzyna A Skorupka, Yueping Wan, Damian Dawidowski, David S Cafiso, Barbie K Ganser-Pornillos, Edward M Campbell, Owen Pornillos
Published 2017-10-01